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Septic embolic encephalitis after Staphylococcus aureus endocarditis of a prosthetic valve in a 57-year-old woman: a case report

机译:一名57岁妇女的人工瓣膜金黄色葡萄球菌心内膜炎后败血症性栓塞性脑炎:一例报告

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For prosthetic heart valves the risk of infection is much higher than for native heart valves. During the course of infective endocarditis 20-40% of all patients suffer from cerebrovascular complications such as ischaemic stroke or intracerebral haemorrhage. We present the case of a 57-year-old woman who had undergone surgery to mechanically replace an aortic heart valve 11 months ago and suffered from repeated ischaemic strokes with secondary haemorrhage. The initial antibiotic regimen was ineffective in treating the later diagnosed Staphylococcus aureus infection of the prosthetic valve. Escalation of the antibiotic treatment was not able to halt the clinical course that finally led to the patient's death. The case report emphasizes the importance of early identification of the aetiology of infection in patients with mechanical heart valve replacement. Without rapid and adequate treatment there is a considerable risk for the development of severe neurological sequelae and cardiac failure that can ultimately result in a fatal course of this clinical picture.
机译:对于人造心脏瓣膜,感染的风险要比天然心脏瓣膜高得多。在传染性心内膜炎的过程中,所有患者中有20-40%患有脑血管并发症,例如缺血性中风或脑出血。我们提供了一个案例,该患者是一名57岁的女性,她在11个月前接受了手术以机械方式置换主动脉心脏瓣膜,并遭受了继发性出血的反复缺血性卒中。最初的抗生素治疗对治疗后来诊断为人工瓣膜的金黄色葡萄球菌感染无效。抗生素治疗的升级并不能阻止最终导致患者死亡的临床过程。病例报告强调了在机械心脏瓣膜置换患者中及早发现感染的病因的重要性。没有快速和充分的治疗,就存在严重的神经系统后遗症和心力衰竭的发展的巨大风险,最终可能导致这种临床情况的致命过程。

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