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首页> 外文期刊>Case Reports in Endocrinology >A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst
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A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst

机译：甲状腺内甲状旁腺囊肿引起的原发性甲状旁腺功能亢进一例

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Parathyroid cysts constitute 0.08–3.41% of all parathyroid masses. Intrathyroidal parathyroid cysts, however, are rare conditions with only a few cases being reported. Most of the parathyroid cysts are found to be nonfunctional and functional cysts are generally thought to be due to cystic degeneration of parathyroid adenomas. A cystic, smooth contoured lesion of 24 × 19 × 16 mm was observed in left thyroid lobe of a 76-year-old woman during ultrasonography which was performed as routine workup for primary hyperparathyroidism. It was defined as a cystic thyroid nodule at first. Tc99msestamibi scintigraphy was performed to see any parathyroid lesions, but no radioactive uptake was observed. Intact parathormone (iPTH) level was found to be >600 pg/mL in cyst aspiration fluid. Left lobectomy was performed, with a diagnosis of primary hyperparathyroidism due to functional parathyroid cyst. Serum iPTH level was decreased >50% postoperatively and histopathological evaluation was consistent with an encapsulated parathyroid adenoma with a cystic center. Parathyroid cysts are among rare causes of primary hyperparathyroidism. Diagnosis is made by markedly increased iPTH level in cyst fluid and observation of parathyroid epithelium lining the cyst wall.
机译：甲状旁腺囊肿占所有甲状旁腺肿块的0.08–3.41％。然而，甲状腺内甲状旁腺囊肿是罕见的疾病，仅报道了少数病例。发现大多数甲状旁腺囊肿是无功能性的，通常认为功能性囊肿是由于甲状旁腺腺瘤的囊性变性所致。在超声检查中，对一名76岁妇女的甲状腺左叶进行了囊性，轮廓光滑的24×19×16 mm病变，这是对原发性甲状旁腺功能亢进症的常规检查。起初它被定义为甲状腺的囊性结节。进行了Tc99msestamibi闪烁显像，以观察到甲状旁腺病变，但未观察到放射性吸收。在囊肿抽吸液中发现完整的副激素（iPTH）水平> 600> pg / mL。进行左叶切除术，诊断为功能性甲状旁腺囊肿引起的原发性甲状旁腺功能亢进。术后血清iPTH水平降低> 50％，组织病理学评价与囊性中心性囊状甲状旁腺腺瘤一致。甲状旁腺囊肿是原发性甲状旁腺功能亢进症的罕见原因之一。诊断通过囊肿液中iPTH水平显着升高和观察囊壁内衬的甲状旁腺上皮来进行。

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