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Multifocal primary tumour with lesions in prostate gland and urinary bladder: clinical case

机译:前列腺和膀胱病变多灶性原发性肿瘤:临床病例

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In some cases a combination of several malignant tumours in one person can be observed. In such case it is the multifocal primary tumour (MPT). The tumours combination in genitourinary system is rare phenomenon, including a rare combination of prostate and urinary bladder cancers. These pathologies can be caused by both the endogenous factors - age, gender, heredity, inflammatory and proliferative processes, abnormal inclusions (calculi and amyloids) and exogenous factors, among which the leading cause is the environmental pollution (heavy metals salts and others), bad habits, occupational hazards, oncogenic viruses and ionizing radiation. A 76 - year- old male patient, Ukrainian, was hospitalized at urology department with complaints on pollakiuria, frequent urinary retention, haematuria appeared about 1 month before. After examination of patient the preliminary diagnosis was made: ?Urinary bladder cancer, acute urinary retention, macrohematuria and posthemorrhagic anemia?. Based on the histological and immunohistochemical examinations, the final diagnosis was determined: combined malignant tumours - acinar adenocarcinoma of prostate index 9 (5 + 4) accordimg to D.F. Gleason and invasive urothelial carcinoma of the urinary bladder. This clinical case demonstrates that the probability of combined oncologic cancer pathology with lesions in one system is rather high. Therefore, in order to exclude the cancer combinations, the patients with malignant tumour in the genitourinary system should undergo a complex examination.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.161-165
机译:在某些情况下,一个人可以观察到多种恶性肿瘤的组合。在这种情况下,它是多灶性原发性肿瘤(MPT)。泌尿生殖系统中的肿瘤组合是罕见的现象,包括前列腺癌和膀胱癌的罕见组合。这些病理可能是由内在因素引起的-年龄,性别,遗传,炎症和增生过程,异常包裹体(结石和淀粉样蛋白)和外源因素,其中主要原因是环境污染(重金属盐等),不良习惯,职业危害,致癌病毒和电离辐射。一名76岁的男性患者,乌克兰人,在泌尿科住院,主诉有尿频,尿频滞留,血尿发生在大约1个月前。对患者进行检查后,初步诊断为:“膀胱癌,急性尿retention留,大血尿和出血后贫血”。根据组织学和免疫组织化学检查,确定最终诊断:合并恶性肿瘤-前列腺腺泡腺癌9(5 + 4)符合D.F。格里森和膀胱浸润性尿路上皮癌。该临床病例表明,在一个系统中将肿瘤肿瘤病理学与病变相结合的可能性相当高。因此,为了排除癌症组合,泌尿生殖系统恶性肿瘤患者应进行复杂检查。孟加拉国医学杂志Vol.16(1)2017 p.161-165

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