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首页> 外文期刊>Bangladesh Journal of Medical Science >Tumor Associated Macrophages-Friends Turned Foe? A Case Report and Review of Literature
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Tumor Associated Macrophages-Friends Turned Foe? A Case Report and Review of Literature

机译:肿瘤相关巨噬细胞-朋友变成敌人了吗?病例报告及文献复习

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摘要

Most malignant tumors are infiltrated by inflammatory cells and it has long been considered that such infiltrates may be evidence of a host response to the tumor. Although lymphocytes are prominent in the inflammatory infiltrate, macrophages are also present, often in considerable numbers. Breast carcinoma is one such tumor where tumor associated macrophages (TAM) have been reported to be widespread, more so in Western literature. There is paucity of information about the biological and prognostic significance of this phenomenon in India. Ours is a tertiary center which receives approximately100 to120cases of breast carcinoma for pathological evaluation annually. Here we report the first case in our experience which showed large numbers of macrophages infiltrating the stroma around the tumor cells.DOI:?http://dx.doi.org/10.3329/bjms.v11i2.8928 Bangladesh Journal of Medical Science Vol. 11 No. 02 April 2012: 139-142
机译:大多数恶性肿瘤都被炎性细胞浸润,长期以来人们一直认为这种浸润可能是宿主对肿瘤反应的证据。尽管淋巴细胞在炎性浸润中突出,但也存在巨噬细胞,通常数量很多。乳腺癌就是这样一种肿瘤,据报道肿瘤相关巨噬细胞(TAM)广泛存在,在西方文献中更是如此。在印度,缺乏有关该现象的生物学和预后意义的信息。我们的第三级中心每年接受大约100至120例乳腺癌进行病理评估。在这里,我们报道了我们的经验中的第一个病例,该病例显示大量巨噬细胞浸润了肿瘤细胞周围的基质。DOI:?http://dx.doi.org/10.3329/bjms.v11i2.8928 2012年4月2日11日:139-142

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