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首页> 外文期刊>Chemotherapy Research and Practice >Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark ofPteleopsis hylodendron(Combretaceae)
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Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark ofPteleopsis hylodendron(Combretaceae)

机译：百日草茎皮甲醇提取物的抗菌和抗氧化性能

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摘要

Pteleopsis hylodendron(Combretaceae) is used in Cameroon and West Africa folk medicine for the treatment of various microbial infections (measles, chickenpox, and sexually transmitted diseases). The antibacterial properties of the methanolic extract and fractions from stem bark ofPteleopsis hylodendronwere tested against three Gram-positive bacteria and eight Gram-negative bacteria using Agar-well diffusion and Broth microdilution methods. Antioxidant activities of the crude extract and fractions were investigated by DPPH radical scavenging activity andβ-carotene-linoleic acid assays. The methanolic extract and some fractions exhibited antibacterial activities that varied between the bacterial species (ID = 0.00–25.00 mm; MIC = 781–12500 μg/mL and 0.24–1000 μg/mL). The activity of the crude extract is, however, very weak compared to the reference antibiotics (MIC = 0.125–128 μg/mL). Two fractions (FEand FF) showed significant activity (MIC = 0.97 μg/mL) whileS. aureusATCC 25922 was almost resistant to all the tested fractions. In addition, the crude extract and some fractions showed good antioxidant potential with inhibition values ranging from 17.53 to 98.79%. These results provide promising baseline information for the potential use of this plant as well as some of the fractions in the treatment of infectious diseases and oxidative stress.
机译：Pteleopsis hylodendron（Combretaceae）在喀麦隆和西非的民间医学中用于治疗各种微生物感染（麻疹，水痘和性传播疾病）。用琼脂孔扩散法和肉汤微稀释法测试了百日草茎皮的甲醇提取物和级分的抗菌性能，对三种革兰氏阳性菌和八种革兰氏阴性菌进行了抗菌测试。通过DPPH自由基清除活性和β-胡萝卜素-亚油酸分析研究了粗提物和馏分的抗氧化活性。甲醇提取物和某些馏分表现出的抗菌活性因细菌种类而异（ID = 0.00–25.00 mm; MIC = 781–12500μg / mL和0.24–1000μg / mL）。但是，与参考抗生素相比，粗提取物的活性非常弱（MIC = 0.125–128μg / mL）。 S和S分别有两个馏分（FE和FF）具有明显的活性（MIC =0.97μg/ mL）。 aureusATCC 25922几乎对所有测试部分均具有抗性。此外，粗提物和某些馏分显示出良好的抗氧化潜能，抑制值范围为17.53至98.79％。这些结果为该植物的潜在用途以及某些部分在治疗传染病和氧化应激中的应用提供了有希望的基线信息。

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