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Factors Affecting the Cost Effectiveness of Antibiotics

机译：影响抗生素成本效益的因素

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In an era of spiraling health care costs and limited resources, policy makers and health care payers are concerned about the cost effectiveness of antibiotics. The aim of this study is to draw on published economic evaluations with a view to identify and illustrate the factors affecting the cost effectiveness of antibiotic treatment of bacterial infections. The findings indicate that the cost effectiveness of antibiotics is influenced by factors relating to the characteristics and the use of antibiotics (i.e., diagnosis, comparative costs and comparative effectiveness, resistance, patient compliance with treatment, and treatment failure) and by external factors (i.e., funding source, clinical pharmacy interventions, and guideline implementation interventions). Physicians need to take into account these factors when prescribing an antibiotic and assess whether a specific antibiotic treatment adds sufficient value to justify its costs.
机译：在医疗保健成本不断飙升和资源有限的时代，决策者和医疗保健支付者都在关注抗生素的成本效益。这项研究的目的是利用已发表的经济评估，以识别和说明影响抗生素治疗细菌感染的成本效益的因素。研究结果表明，抗生素的成本效益受与抗生素的特性和使用有关的因素（即诊断，比较成本和比较效力，耐药性，患者对治疗的依从性和治疗失败）的影响以及外部因素（即，资金来源，临床药学干预措施以及指南实施干预措施）。医师在开抗生素时需要考虑这些因素，并评估特定的抗生素治疗是否增加了足够的价值以证明其成本合理。

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