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Drosophila melanogaster as a model for basal body research

机译：果蝇作为基础身体研究的模型

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The fruit fly, Drosophila melanogaster, is one of the most extensively studied organisms in biological research and has centrioles/basal bodies and cilia that can be modelled to investigate their functions in animals generally. Centrioles are nine-fold symmetrical microtubule-based cylindrical structures required to form centrosomes and also to nucleate the formation of cilia and flagella. When they function to template cilia, centrioles transition into basal bodies. The fruit fly has various types of basal bodies and cilia, which are needed for sensory neuron and sperm function. Genetics, cell biology and behaviour studies in the fruit fly have unveiled new basal body components and revealed different modes of assembly and functions of basal bodies that are conserved in many other organisms, including human, green algae and plasmodium. Here we describe the various basal bodies of Drosophila , what is known about their composition, structure and function.
机译：果蝇果蝇（Drosophila melanogaster）是生物学研究中研究最广泛的有机体之一，具有中心粒/基体和纤毛，可通过建模来研究它们在动物中的总体功能。质心是形成中心体并成核纤毛和鞭毛所需的九倍对称的基于微管的圆柱形结构。当它们起到模板纤毛的作用时，中心粒转变为基体。果蝇具有各种类型的基体和纤毛，这是感觉神经元和精子功能所必需的。果蝇的遗传学，细胞生物学和行为研究揭示了新的基体成分，并揭示了在许多其他生物体（包括人，绿藻和疟原虫）中保守的基体的组装模式和功能。在这里，我们描述了果蝇的各种基体，有关它们的组成，结构和功能的知识。

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