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首页> 外文期刊>Circulation journal >Gender and Age Differences in Candidates for Radiofrequency Catheter Ablation of Idiopathic Ventricular Arrhythmias
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Gender and Age Differences in Candidates for Radiofrequency Catheter Ablation of Idiopathic Ventricular Arrhythmias

机译：特发性室性心律失常的射频消融候选者的性别和年龄差异

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Background: The prevalence, gender- and age-related differences, ablation success rate and inter-relationship between the origins of the idiopathic ventricular arrhythmias (I-VA) have not been clarified. Methods and Results: A total of 625 consecutive patients with symptomatic, drug resistant I-VA (315 males and 310 females; mean age, 54±17 years; 218 ventricular tachycardias, 407 premature ventricular contractions) who underwent catheter ablation were studied. The patients were divided into 5 groups based on the VA origin: (1) outflow tract (OT)-VA, consisting of right ventricular (RV) OT-VA and left ventricular (LV) OT-VA; (2) inflow tract (IT)-VA, consisting of tricuspid annulus (TA)-free wall (FW)-VA, IT-septum-VA, and mitral (MA)-FW-VA; (3) LV-inferoseptum-VA; (4) LV-other-VA; and (5) RV-other-VA. RVOT-VA in women were 1.5 times more frequent than in men, while LVOT-VA were more frequent in men. The prevalence of LVOT origin I-VA increased with age compared to that for the RVOT. The mean age of MA-FW-VA patients (62±14 years) was higher than that of TA-FW-VA patients (51±18 years; P=0.03). The ablation success rate for RVOT-VA (88%) was higher than that for LVOT-VA (58%; P
机译：背景：特发性室性心律失常（I-VA）的发病率，性别和年龄相关的差异，消融成功率以及相互之间的关系尚未阐明。方法和结果：研究了总共625例有症状，耐药的I-VA患者（男性315例，女性310例;平均年龄54±17岁; 218例室性心动过速，407例室性早搏）。根据VA的来源将患者分为5组：（1）流出道（OT）-VA，由右心室（RV）OT-VA和左心室（LV）OT-VA组成; （2）流入管道（IT）-VA，由无三尖瓣环（TA）的壁（FW）-VA，IT-隔膜-VA和二尖瓣（MA）-FW-VA组成; （3）LV-inferoseptum-VA; （4）LV-other-VA; （5）RV-other-VA。女性的RVOT-VA的发生频率是男性的1.5倍，而男性的LVOT-VA的发生频率更高。与RVOT相比，起源于LVOT的I-VA患病率随年龄增加。 MA-FW-VA患者的平均年龄（62±14岁）高于TA-FW-VA患者的（51±18岁; P = 0.03）。 RVOT-VA的消融成功率（88％）高于LVOT-VA（58％; P

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