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首页> 外文期刊>Circulation journal >Abnormal Left Ventricular Vortex Flow Patterns in Association With Left Ventricular Apical Thrombus Formation in Patients With Anterior Myocardial Infarction – A Quantitative Analysis by Contrast Echocardiography –
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Abnormal Left Ventricular Vortex Flow Patterns in Association With Left Ventricular Apical Thrombus Formation in Patients With Anterior Myocardial Infarction – A Quantitative Analysis by Contrast Echocardiography –

机译:前部心肌梗死患者左心室涡流异常与左室心尖血栓形成的关系–超声心动图定量分析–

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Background: ?The current study was designed to investigate the correlation between the left ventricular (LV) vortex flow pattern and LV apical thrombus formation in patients with acute anterior wall myocardial infarction (MI). Methods and Results: ?Fifty-seven patients with acute anterior wall MI were enrolled in this study. Eighteen patients with apical thrombus (thrombus group) and 39 patients without apical thrombus (non-thrombus group) underwent 2-dimensional contrast echocardiography (CE). Morphology and pulsatility parameters of the LV vortex were measured using Omega flow? and compared between the 2 groups. In the thrombus group, the vortex was located more centrally and did not extend to the apex. In the thrombus group, quantitative vortex parameters of vortex depth (0.409±0.101 vs. 0.505±0.092, respectively; P=0.002) and relative strength (1.574±0.310 vs. 1.808±0.376, respectively, P=0.034) were significantly lower than the non-thrombus group. Following multivariate analysis, the vortex depth below 0.45 remained a significant independent parameter for formation of the LV apical thrombus (odds ratio 9.714, 95% confidence interval 1.674–56.381, P=0.011). Conclusions: ?These findings suggest that the location and pulsatility power of the LV vortex are strongly associated with the LV thrombus formation in patients with anterior MI. Therefore, LV vortex flow analysis using CE can be clinically useful for characterizing and quantifying the risk of LV apical thrombus in patients with anterior MI.??(Circ J?2012; 76: 2640–2646)
机译:背景:本研究旨在研究急性前壁心肌梗死(MI)患者左心室(LV)涡流模式与左心尖血栓形成之间的相关性。方法和结果:这项研究纳入了57例急性前壁心肌梗死患者。 18例顶端血栓患者(血栓组)和39例非顶端血栓患者(非血栓组)接受了二维超声心动图检查(CE)。使用Omega flow ?测量LV涡旋的形态和脉动参数,并在两组之间进行比较。在血栓组中,涡流位于更中央,没有延伸到顶点。在血栓组中,涡旋深度的定量涡旋参数(分别为0.409±0.101和0.505±0.092; P = 0.002)和相对强度(分别为1.574±0.310和1.808±0.376,P = 0.034)显着低于非血栓组。经过多变量分析后,低于0.45的涡旋深度仍然是形成左心尖血栓的重要独立参数(优势比9.714,95%置信区间1.674–56.381,P = 0.011)。结论:这些发现表明左心室旋流的位置和脉动能力与前心梗患者左心室血栓形成密切相关。因此,使用CE进行LV涡流分析在临床上可用于表征和量化MI前期患者左心尖血栓的风险。(Circ J?2012; 76:2640-2646)

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