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Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

机译:左心房扩张指数预测呼吸困难的心房颤动

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Background: ?The left atrial (LA) expansion index for predicting atrial fibrillation (AF) in a relatively low-risk cohort is not fully understood. Methods and Results: ?In this prospective study of 2,200 dypnea patients, the LA expansion index was calculated as (Volmax–Volmin)×100%/Volmin, where Volmax was defined as maximum LA volume and Volmin was defined as minimum volume. The endpoints were 2-year frequency of AF, including both paroxysmal and persistent. Of the 180 participants (8.2%) who had AF attacks over a median follow-up of 2.7 years, 90 (4.1%) had at least 1 episode of persistent AF. Compared to patients with paroxysmal AF, those with persistent AF had a much lower LA expansion index (100±59% vs. 44±24%). LA expansion index was associated exponentially with the incidence of persistent AF. Independent predictors of AF included age, renal function impairment, pulmonary artery systolic pressure, and LA expansion index. Persistent AF, however, had significant independent associations only with prior heart failure, renal function impairment, diastolic dysfunction, and LA expansion index (odds ratio, 0.970; 95% confidence interval: 0.959–0.981 per 1% increase, P
机译:背景:?在相对低风险的人群中,用于预测房颤(AF)的左心房(LA)扩张指数尚未完全了解。方法和结果:在这项对2200例呼吸困难患者的前瞻性研究中,LA扩张指数计算为(Vol max –Vol min )×100%/ Vol min ,其中将Vol max 定义为最大LA体积,将Vol min 定义为最小LA体积。终点为两年的房颤发生频率,包括阵发性和持续性。在中位随访时间为2.7年的180名参与者(8.2%)发生房颤发作,其中90名(4.1%)患有至少1次持续性房颤发作。与阵发性AF患者相比,持续性AF患者的LA扩张指数低得多(100±59%比44±24%)。洛杉矶扩张指数与持续性房颤的发生呈指数相关。 AF的独立预测因子包括年龄,肾功能损害,肺动脉收缩压和LA扩张指数。然而,持续性房颤仅与先前的心力衰竭,肾功能损害,舒张功能障碍和LA扩张指数有显着的独立关联(比值,0.970; 95%置信区间:每增加1%,P值为0.959-0.981,P

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