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首页> 外文期刊>Circulation journal >Optimal Strength and Number of Shocks at Upper Limit of Vulnerability Testing Required to Predict High Defibrillation Threshold Without Inducing Ventricular Fibrillation
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Optimal Strength and Number of Shocks at Upper Limit of Vulnerability Testing Required to Predict High Defibrillation Threshold Without Inducing Ventricular Fibrillation

机译：在不导致心室纤颤的情况下预测高除颤阈值所需的脆弱性测试上限的最佳强度和电击次数

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Background: ?The upper limit of vulnerability (ULV) closely correlates with the defibrillation threshold (DFT). The aim of this study was to establish the optimal protocol for using the ULV test to predict high DFT (>20J) without inducing ventricular fibrillation (VF). Methods and Results: ?The 10-J and 15-J ULV test with 3 coupling intervals (–20, 0, and +20ms to the peak of T-wave) and the DFT test were performed in 96 patients receiving implantable cardioverter defibrillator. ULV ≤10J was confirmed in 47 (49%). ULV ≤15J was confirmed in 70 (77%) of 91 patients (15-J ULV test could not be done in 5). The sensitivity and negative predictive value of both ULV >10J and >15J for predicting high DFT were 100%. The specificity and positive predictive value of ULV >15J were higher than those for ULV >10J (85% vs. 55%, 43% vs. 22%, respectively). The rate of VF inducibility for confirming ULV ≤15J was lower than that for ULV ≤10J (23% vs. 51%, P
机译：背景：？脆弱性上限（ULV）与除颤阈值（DFT）密切相关。这项研究的目的是为使用ULV测试预测高DFT（> 20J）而不会引起心室纤颤（VF）建立最佳方案。方法和结果：96例接受植入式心脏复律除颤器的患者进行了10-J和15-J ULV测试，每3次耦合间隔（到T波的峰值分别为–20、0和+ 20ms）和DFT测试。在47（49％）中证实ULV≤10J。在91例患者中有70例（77％）证实了ULV≤15J（5例中无法进行15-J ULV测试）。 ULV> 10J和> 15J两者对预测高DFT的敏感性和阴性预测值为100％。 ULV> 15J的特异性和阳性预测值高于ULV> 10J的特异性和阳性预测值（分别为85％对55％，43％对22％）。确认ULV≤15J的VF诱导率低于ULV≤10J的VF诱导率（23％vs. 51％，P

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