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首页> 外文期刊>Circulation journal >Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients With Heart Failure
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Acute Hemodynamic Effects of Adaptive Servo-Ventilation in Patients With Heart Failure

机译：自适应伺服通气对心力衰竭患者的急性血流动力学影响

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Background: ?Adaptive servo-ventilation (ASV) improves cardiac function in patients with heart failure (HF). We compared the hemodynamics of control and HF patients, and identified the predictors for acute effects of ASV in HF. Methods and Results: ?We performed baseline echocardiographic measurements and hemodynamic measurements at baseline and after 15min of ASV during cardiac catheterization in 11 control and 34 HF patients. Heart rate and blood pressure did not change after ASV in either the control or HF group. Stroke volume index (SVI) decreased from 49.3±7.6 to 41.3±7.6ml/m2 in controls (P2, P=0.148). In the univariate analysis, pulmonary capillary wedge pressure (PCWP), mitral regurgitation (MR)/left atrial (LA) area, E/A, E/e’, and the sphericity index defined by the ratio between the short-axis and long-axis dimensions of the left ventricle significantly correlated with % change of SVI from baseline during ASV. PCWP and MR/LA area were independent predictors by multivariate analysis. Moreover, responders (15 of 34 HF patients; 44%) categorized by an increase in SVI showed significantly higher PCWP, MR, and sphericity index. Conclusions: ?Left ventricular structure and MR, as well as PCWP, could predict acute favorable effects on hemodynamics by ASV therapy in HF patients.??(Circ J?2013; 77: 1214–1220)
机译：背景：？自适应伺服通气（ASV）改善心力衰竭（HF）患者的心功能。我们比较了对照组和HF患者的血液动力学，并确定了ASV在HF中急性作用的预测因素。方法和结果：？我们对11例对照和34例HF患者进行了基线超声心动图测量和血液动力学测量，分别在基线和ASV 15分钟后的心脏导管插入期间进行。对照组或HF组中ASV后的心率和血压均未改变。对照的中风体积指数（SVI）从49.3±7.6降至41.3±7.6ml / m 2 （P2 ，P = 0.148）。在单变量分析中，肺毛细血管楔压（PCWP），二尖瓣反流（MR）/左心房（LA）面积，E / A，E / e'和由短轴与长轴之比定义的球形度指数在ASV期间，左心室的心轴尺寸与SVI相对于基线的百分比变化显着相关。通过多变量分析，PCWP和MR / LA面积是独立的预测因子。此外，按SVI升高分类的应答者（34例HF患者中的15例; 44％）显示PCWP，MR和球度指数明显更高。结论：左心室结构和MR以及PCWP可以预测ASV治疗对HF患者的血液动力学的急性有利影响。（Circ J？2013; 77：1214-1220）

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