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首页> 外文期刊>Circulation journal >Short-Term Change in Gait Speed and Clinical Outcomes in Older Patients With Acute Heart Failure
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Short-Term Change in Gait Speed and Clinical Outcomes in Older Patients With Acute Heart Failure

机译：老年急性心力衰竭患者的步态速度和临床结果的短期变化

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Background: Evidence for the prognostic value of gait speed is largely based on a single measure at baseline, so we investigated the prognostic significance of change in gait speed in hospitalized older acute heart failure (AHF) patients. Methods?and?Results: This retrospective study was performed in a cohort of 388 AHF patients ≥60 years old (mean age: 74.8±7.8 years, 228 men). Routine geriatric assessment included gait speed measurement at baseline and at discharge. The primary outcome of this study was all-cause death. Gait speed increased from 0.74±0.25 m/s to 0.98±0.27 m/s after 13.5±11.0 days. Older age, shorter height and lower hemoglobin level at admission, prior HF admission, and higher baseline gait speed were independently associated with lesser improvement in gait speed. A total of 80 patients died and 137 patients were readmitted for HF over a mean follow-up period of 2.1±1.9 years. In multivariate analyses, change in gait speed showed inverse associations with all-cause death (hazard ratio [HR] per 0.1 m/s increase: 0.83; 95% confidence interval [CI]: 0.73 to 0.95; P=0.006) and with risk of readmission for HF (HR: 0.91; 95% CI: 0.83 to 0.99; P=0.036). Conclusions: Short-term improvement in gait speed during hospitalization was associated with reduced risks of death and readmission for HF in older patients with AHF.
机译：背景：步态速度预后价值的证据主要基于基线时的单一测量，因此我们研究了住院老年急性心力衰竭（AHF）患者步态速度变化的预后意义。方法和结果：这项回顾性研究是在队列研究中对388名≥60岁的AHF患者（平均年龄：74.8±7.8岁，228名男性）进行的。常规的老年评估包括基线和出院时的步态速度测量。这项研究的主要结果是全因死亡。 13.5±11.0天后，步态速度从0.74±0.25 m / s增加到0.98±0.27 m / s。年龄较大，入院时身高矮，血红蛋白水平低，入院前先HF和较高的基线步态速度独立地与步态速度改善较小有关。在2.1±1。9年的平均随访期内，共有80名患者死亡，并有137名患者再次接受HF治疗。在多变量分析中，步态速度的变化与全因死亡呈负相关（风险比[HR]每0.1 m / s增加：0.83; 95％置信区间[CI]：0.73至0.95; P = 0.006）和风险HF再入院率（HR：0.91; 95％CI：0.83至0.99; P = 0.036）。结论：住院期间步态速度的短期改善与老年AHF患者的HF死亡和再次入院风险降低有关。

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