...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Circulation journal >Endarteritis Obliterans in the Pathogenesis of Buerger’s Disease From the Pathological and Immunohistochemical Points of View
【24h】

Endarteritis Obliterans in the Pathogenesis of Buerger’s Disease From the Pathological and Immunohistochemical Points of View

机译：从病理学和免疫组化的角度看闭塞性动脉炎闭塞性细菌在Buerger病发病机理中的作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Buerger’s disease (thromboangiitis obliterans) is considered to be a nonatherosclerotic, inflammatory, and vaso-occlusive disease, although the details of the mechanisms of pathogenesis remain unknown. The occurrence of the disease is strongly related to tobacco abuse and its progression is closely linked to continued smoking. The purpose of this review article is to demonstrate the pathological characteristics of arteries affected with Buerger’s disease from a possible immunoreactive point of view. In addition, we present the mechanisms for preserving the architecture of the arterial wall in affected vasculatures. Thereafter, we discuss the possibility that the pathogenesis of Buerger’s disease is a type of endarteritis obliterans, deeply connected to the Notch pathway, distinct from arteriosclerosis obliterans and other vasculitides. ( Circ J 2014; 78: 2819–2826)
机译：尽管尚不清楚致病机理的详细信息，但Buerger病（闭塞性血栓性血管炎）被认为是一种非动脉粥样硬化，炎性和血管闭塞性疾病。该病的发生与烟草滥用密切相关，其进展与持续吸烟密切相关。这篇综述文章的目的是从可能的免疫反应角度，证明感染了布尔格病的动脉的病理特征。此外，我们介绍了在受影响的脉管系统中保留动脉壁结构的机制。此后，我们讨论了Buerger病的发病机制是一种闭塞性内膜炎的可能性，它与Notch通路密切相关，不同于闭塞性动脉硬化症和其他血管炎。 （Circ J 2014; 78：2819–2826）

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号