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首页> 外文期刊>Case Reports in Medicine >Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma
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Recurrent Plasmacytomas after Allografting in a Patient with Multiple Myeloma

机译：多发性骨髓瘤患者同种异体移植后复发性浆细胞瘤

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Extramedullary recurrence in multiple myeloma patients has been reported after both autologous and allogeneic hematopoietic cell transplantation and, more recently, after treatment with so-called new drugs with potent antimyeloma activity. Only a very few sizable reports focused on its clinical presentation and its incidence, which may be highly underestimated, and most observations are based on single patients reported from several institutions. Given the unusual sites of recurrence, diagnosis may be rather difficult and delayed treatment may play a relevant role in prognosis. Here we report a case of a myeloma patient, initially treated with an allograft, who enjoyed an eleven-year disease-free remission with very good quality of life. She eventually relapsed first with an extramedullary plasmacytoma in the breast and, two years later, with a right atrial cardiac mass.
机译：自体和同种异体造血细胞移植后以及最近，在使用具有有效抗骨髓瘤活性的所谓新药治疗后，已有多发性骨髓瘤患者发生髓外复发的报道。只有极少数的报告关注其临床表现和发病率，而这些报告可能被低估了，并且大多数观察结果是基于多家机构报告的单例患者。考虑到异常的复发部位，诊断可能相当困难，延迟治疗可能在预后中起重要作用。在这里，我们报道了一名骨髓瘤患者，该患者最初接受了同种异体移植治疗，该患者十一年无病缓解，生活质量非常好。最终她首先因乳房髓外浆细胞瘤复发，两年后因右心房心脏质量复发。

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