...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Case Reports in Obstetrics and Gynecology >Fetal Tachycardia Treated Successfully with Maternally Administered Propylthiouracil
【24h】

Fetal Tachycardia Treated Successfully with Maternally Administered Propylthiouracil

机译：孕产妇给予丙硫氧嘧啶成功治疗胎儿心动过速

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background. Fetal tachycardia may result from the transplacental passage of thyroid stimulating immunoglobulins in a patient with hypothyroidism secondary to ablation of Graves’ disease.Case. A 32-year-old woman, gravida 4, para 2, and abortus 1, with hypothyroidism and a history of Graves’ disease, presented at 23 6/7 weeks of gestation with a persistent fetal tachycardia. The treatment of the fetal tachycardia with maternally administered digoxin and Sotalol was unsuccessful. Maternal thyroid stimulating immunoglobulins were elevated, and treatment with maternally administered propylthiouracil (PTU) resulted in a normal sinus rhythm for the remainder of the pregnancy. An induction of labor was performed at 37 weeks. Four to five days after delivery, the neonate exhibited clinical signs of hyperthyroidism necessitating treatment.Conclusion. Fetal tachycardia resulting from the transplacental passage of thyroid stimulating immunoglobulins can be successfully treated with maternally administered PTU. The neonate needs to be followed up closely as clinical signs of hyperthyroidism may occur as thyroid stimulating immunoglobulins continue to circulate in the neonate, while the serum levels of PTU decline.
机译：背景。继发于Graves病消融的甲状腺功能减退患者中，甲状腺刺激性免疫球蛋白经甲状腺经胎盘传递可能导致胎儿心动过速。妊娠23 6/7周时出现持续性胎儿心动过速的32岁妇女，孕妇gravida 4，para 2，流产1，有甲状腺功能减退和Graves病史。母体使用地高辛和索他洛尔治疗胎儿心动过速失败。孕产妇甲状腺刺激性免疫球蛋白升高，而孕产妇服用丙硫氧嘧啶（PTU）进行治疗可使妊娠剩余时间的窦性心律正常。在第37周进行引产。分娩后四到五天，新生儿表现出甲状腺功能亢进的临床体征，需要进行治疗。甲状腺刺激性免疫球蛋白经胎盘传递而引起的胎儿心动过速可以通过母体给予的PTU成功治疗。新生儿需要密切随访，因为甲状腺刺激性免疫球蛋白继续在新生儿中流通，同时血清PTU水平下降，可能会出现甲亢的临床体征。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号