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首页> 外文期刊>Case Reports in Obstetrics and Gynecology >Successful Laparoscopic Resection of 7 mm Ovarian Mature Cystic Teratoma Associated with Anti-NMDAR Encephalitis
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Successful Laparoscopic Resection of 7 mm Ovarian Mature Cystic Teratoma Associated with Anti-NMDAR Encephalitis

机译：腹腔镜成功切除7mm卵巢成熟囊性畸胎瘤并伴有抗NMDAR脑炎

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摘要

Anti-NMDAR (N-methyl-D-aspartate receptor) encephalitis is an immune-mediated encephalitis. It has been predominantly described in young women and is commonly associated with an ovarian teratoma. We report a case of anti-NMDAR encephalitis associated with a 7 mm ovarian teratoma that was completely resected by laparoscopic surgery. An 18-year-old woman suddenly presented with personality changes requiring her admission to the department of neurology. After that, she also showed involuntary movements, disturbance of consciousness, and central hypoventilation. As an abdominal image revealed the possibility of a right ovarian teratoma of5×7 mm, a laparoscopic operation was performed. The macroscopic appearance of the right ovary did not show any abnormalities; nevertheless, we performed a partial resection of the right ovary, with reference to the image diagnosis, in order to spare the ovarian reserve. The22×22 mm partially resected ovary contained an intact5×7 mm cystic tumor. The pathological diagnosis was mature cystic teratoma with components of brain tissue. An anti-NMDAR-antibody test proved positive in both serum and cerebrospinal fluid 1 month after the surgery. From these results, she was diagnosed with anti-NMDAR encephalitis. By the administration of cyclophosphamide in addition to the operation, she recovered drastically without any of the symptoms shown before.
机译：抗NMDAR（N-甲基-D-天冬氨酸受体）脑炎是一种免疫介导的脑炎。它主要在年轻女性中描述，通常与卵巢畸胎瘤相关。我们报告了一例经腹腔镜手术完全切除的与7 mm卵巢畸胎瘤有关的抗NMDAR脑炎。一名18岁妇女突然出现性格改变，要求她进入神经内科。此后，她还表现出不自主运动，意识障碍和中央通风不足。由于腹部图像显示出右侧卵巢畸胎瘤可能为5×7 mm，因此进行了腹腔镜手术。右卵巢的宏观外观未显示任何异常。尽管如此，我们还是参考影像学诊断对右侧卵巢进行了部分切除，以保留卵巢储备。部分切除的22×22 mm卵巢中有完整的5×7 mm囊性肿瘤。病理诊断为具有脑组织成分的成熟囊性畸胎瘤。手术后1个月，抗NMDAR抗体测试在血清和脑脊液中均呈阳性。根据这些结果，她被诊断出患有抗NMDAR脑炎。除了手术外，她还服用了环磷酰胺，使她彻底康复，没有出现任何以前出现的症状。

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