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首页> 外文期刊>Clinical ophthalmology >Successful treatment of syphilitic uveitis in HIV-positive patients
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Successful treatment of syphilitic uveitis in HIV-positive patients

机译：HIV阳性患者梅毒性葡萄膜炎的成功治疗

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Abstract: We report successful treatment of syphilitic uveitis in a case series of three Human immunodeficiency virus (HIV)-positive patients at Malaysia's Selayang Hospital eye clinic. All three patients with syphilitic uveitis were male, aged from 23 to 35 years old, with a history of high-risk behaviors. Of the patients, two presented with blurring of vision and only one patient presented with floaters in the affected eye. Ocular examination revealed intermediate uveitis (case 1 and case 3) and panuveitis (case 2). Each patient showed a high Venereal Disease Research Laboratory (VDRL) titer at presentation and they were also newly diagnosed as HIV positive with variable CD4 counts. All three patients responded well to a neurosyphilis regimen of intravenous penicillin G. At 3 months posttreatment, there was reduction in VDRL titer with improvement of vision in the affected eye. Diagnosis of syphilis needs to be ruled out in all cases of uveitis. All syphilitic uveitis cases should have HIV screening and vice versa, as syphilis is one of the most common infectious diseases associated with HIV-positive patients. Early detection and treatment are important for a good visual outcome.
机译：摘要：我们报道了在马来西亚的Selayang医院眼科诊所对三名人类免疫缺陷病毒（HIV）阳性患者进行了一系列病例治疗，成功治疗了梅毒性葡萄膜炎。三名梅毒性葡萄膜炎患者均为男性，年龄在23至35岁之间，具有高危行为史。在这些患者中，有两名患者出现视力模糊，只有一名患者在受影响的眼睛中出现了漂浮物。眼科检查显示中度葡萄膜炎（病例1和病例3）和胰腺炎（病例2）。每位患者表现出高的性病研究实验室（VDRL）滴度，并且他们也被新诊断为HIV阳性且CD4计数可变。所有三名患者对静脉注射青霉素G的神经梅毒方案反应良好。治疗后3个月，患眼的VDRL滴度降低，视力提高。在所有葡萄膜炎病例中都需要排除梅毒的诊断。所有梅毒葡萄膜炎病例都应进行HIV筛查，反之亦然，因为梅毒是与HIV阳性患者相关的最常见的传染病之一。早期发现和治疗对于良好的视觉效果非常重要。

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