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Magnesium in disease

机译：镁在疾病中

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Although the following text will focus on magnesium in disease, its role in healthy subjects during physical exercise when used as a supplement to enhance performance is also noteworthy. Low serum magnesium levels are associated with metabolic syndrome, Type 2 diabetes mellitus (T2DM) and hypertension; consequently, some individuals benefit from magnesium supplementation: increasing magnesium consumption appears to prevent high blood pressure, and higher serum magnesium levels are associated with a lower risk of developing a metabolic syndrome. There are, however, conflicting study results regarding magnesium administration with myocardial infarction with and without reperfusion therapy. There was a long controversy as to whether or not magnesium should be given as a first-line medication. As the most recent trials have not shown any difference in outcome, intravenous magnesium cannot be recommended in patients with myocardial infarction today. However, magnesium has its indication in patients with torsade de pointes and has been given successfully to patients with digoxin-induced arrhythmia or life-threatening ventricular arrhythmias. Magnesium sulphate as an intravenous infusion also has an important established therapeutic role in pregnant women with pre-eclampsia as it decreases the risk of eclamptic seizures by half compared with placebo.
机译：尽管以下内容将重点放在疾病中的镁上，但当镁作为补充品来增强体力时，它在体育锻炼中对健康受试者的作用也值得注意。血清镁水平低与代谢综合征，2型糖尿病（T2DM）和高血压有关。因此，一些人受益于补充镁：增加镁的摄入似乎可以预防高血压，而较高的血清镁水平与发生代谢综合征的风险较低有关。然而，关于在有或没有再灌注治疗的情况下，在心肌梗死中服用镁的研究结果相互矛盾。关于是否应将镁作为一线药物存在长期争议。由于最新的试验尚未显示出任何结果差异，因此今天不建议在心肌梗塞患者中推荐静脉使用镁。然而，镁已在尖端扭转型室速患者中得到了适应症，并且已成功地用于患有地高辛引起的心律不齐或危及生命的室性心律不齐的患者。作为先兆子痫的孕妇，硫酸镁作为静脉内输液也具有重要的已确立的治疗作用，因为与安慰剂相比，其将先兆子痫发作的风险降低了一半。

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