Neurofibromatosis type 1-associated hypertension secondary to coarctation of the thoracic aorta

Gaurang Mavani; Jordan L. Rosenstock; Joshua A. Schwimmer; Maria V. Devita; Michael F. Michelis; Vivek Kesar

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Neurofibromatosis type 1-associated hypertension secondary to coarctation of the thoracic aorta

机译：继发于胸主动脉缩窄的1型神经纤维瘤病相关高血压

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Neurofibromatosis type 1 (NF-1), also known as von Recklinghausen's disease, is an autosomal dominant genetic disorder. NF-I vasculopathy has been used to describe various vascular malformations associated with NF-1. Secondary hypertension related to NF-1 vasculopathy has been reported because of renal artery stenosis, coarctation of the abdominal aorta and other vascular lesions; however, coarctation of the thoracic aorta has seldom been reported. We report the first case, to our knowledge, of isolated coarctation of thoracic aorta in a pregnant female with NF-1. Healthcare providers caring for patients with NF-1 should be aware of associated vascular complications.

机译：1型神经纤维瘤病（NF-1），也称为冯·雷克林豪森氏病，是一种常染色体显性遗传疾病。 NF-1血管病变已被用于描述与NF-1相关的各种血管畸形。由于肾动脉狭窄，腹主动脉缩窄和其他血管病变，已报告了与NF-1血管病有关的继发性高血压。然而，很少有胸主动脉缩窄的报道。据我们所知，我们报道了第一例患有NF-1的怀孕女性的胸主动脉缩窄。照顾NF-1患者的医疗保健提供者应注意相关的血管并发症。

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《Clinical kidney journal.》 |2014年第4期|共2页
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Gaurang Mavani; Jordan L. Rosenstock; Joshua A. Schwimmer; Maria V. Devita; Michael F. Michelis; Vivek Kesar;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Neurofibromatosis type 1-associated hypertension secondary to coarctation of the thoracic aorta [J] . MavaniG., KesarV., DevitaM.V., Clinical kidney journal . 2014,第4期

机译：继发于胸主动脉缩窄的1型神经纤维瘤病相关高血压
2. Neurofibromatosis Type 1 Complicated by Atypical Coarctation of the Thoracic Aorta [J] . MasatoKimura, ShuheiKakizaki, KengoKawano, Case Reports in Pediatrics . 2013,第3期

机译：1型神经纤维瘤病并发胸主动脉缩窄
3. A case of coarctation of the abdominal aorta and renal artery stenosis due to neurofibromatosis type 1 [J] . Veean Satyam, Thakkar Nancy, Gupta Supriya, Postgraduate Medical Journal . 2018,第1098期

机译：由于神经纤维瘤病引起的腹部主动脉和肾动脉狭窄的造成的案例
4. Effect of hypertension on contractile and mechanical properties of smooth muscle cells isolated from rat thoracic aortas [C] . Takeo Matsumoto, Mitsunobu Yamamoto, Shinji Seo, Bioengineering Conference . 2001

机译：高血压对大鼠胸部主动脉分离的平滑肌细胞收缩与力学性能的影响
5. Exploiting neurofibromatosis type 1-associated cancer models to identify novel therapeutic targets [D] . Johannessen, Cory Matthew 2008

机译：利用与1型神经纤维瘤病相关的癌症模型确定新的治疗靶标
6. Neurofibromatosis type 1-associated hypertension secondary to coarctation of the thoracic aorta [O] . Gaurang Mavani, Vivek Kesar, Maria V. Devita, 2014

机译：继发于胸主动脉缩窄的1型神经纤维瘤病相关高血压
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Neurofibromatosis type 1-associated hypertension secondary to coarctation of the thoracic aorta

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