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首页> 外文期刊>Clinical, Cosmetic and Investigational Dermatology >Complete biodegradable nature of calcium hydroxylapatite after injection for malar enhancement: an MRI study
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Complete biodegradable nature of calcium hydroxylapatite after injection for malar enhancement: an MRI study

机译：注射用于增强黄斑的羟磷灰石钙的完全可生物降解性质：MRI研究

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Background: Radiesse? (Calcium hydroxylapatite [CaHA]) is a biocompatible, injectable gel for facial soft tissue augmentation. It is a completely biodegradable filler and this is well documented, but objective imaging methods to confirm this property are scarce.Methods: We present a case report in which CaHA was injected into the midface of a 50-year-old woman for volume restoration and shaping of the cheek region. On the right side of the face, 1.6 mL CaHA was injected as several (5-7) small depots (0.1-0.2 mL) using a 28G 3/4 inch needle and the vertical supraperiosteal depot technique. On the contralateral side of the face, the subject received 1.6 mL CaHA over three entry points using a 27G 1 1/2 inch blunt cannula and the fanning technique. CaHA location and degradation were assessed using magnetic resonance imaging (MRI).Results: CaHA appears as low-to-intermediate signal intensity on MRI images taken immediately after injection for malar enhancement with a symmetrical distribution. On MRI images taken 2.5 years after injection, no CaHA was visible but tissue volume remained increased, indicating a collagen-stimulating effect. The treatment was well tolerated.Conclusion: In addition to producing long-lasting aesthetic and collagen-stimulating effects, MRI images confirm that CaHA is completely biodegradable with no product remaining 2.5 years after injection.
机译：背景：蕾迪丝？ （羟磷灰石钙[CaHA]）是一种生物相容性，可注射的凝胶，可用于面部软组织增强。它是一种完全可生物降解的填充剂，有据可查，但缺乏确定这种性质的客观成像方法。方法：我们提供了一例病例报告，其中将CaHA注射到一名50岁女性的中面部，以进行体积修复和修复。脸颊区域的塑造。在脸部右侧，使用28G 3/4英寸针头和垂直骨膜上储库技术将1.6 mL CaHA作为几个（5-7）小储库（0.1-0.2 mL）注射。在面部的对侧，受试者使用27G 1 1/2英寸钝套管和散开技术在三个进入点接受1.6 mL CaHA。结果：CaHA在注射以对称分布的黄斑增强后立即拍摄的MRI图像上表现为中低信号强度。在注射后2.5年拍摄的MRI图像上，看不到CaHA，但组织体积仍然增加，表明具有胶原蛋白刺激作用。结论：除产生持久的美学效果和胶原蛋白刺激作用外，MRI图像还证实CaHA是完全可生物降解的，注射后2.5年内没有残留任何产品。

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