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Outcomes of Ahmed glaucoma valve implantation in advanced primary congenital glaucoma with previous surgical failure

机译:艾哈迈德青光眼瓣膜植入术治疗晚期原发性先天性青光眼并手术失败的结果

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Purpose: The purpose of this study was to evaluate the intermediate surgical results of Ahmed glaucoma valve (AGV) implantation in patients less than 7 years of age, with advanced primary congenital glaucoma who have failed previous surgeries.Patients and methods: Consecutive patients with advanced primary congenital glaucoma that failed previous operations and had undergone subsequent AGV implantation were evaluated retrospectively. Surgical success was defined as 1) intraocular pressure (IOP) ≥6 and?≤21?mmHg; 2) IOP reduction of at least 30% relative to preoperative values; and 3) without the need for additional surgical intervention for IOP control, loss of light perception, or serious complications.Results: Fourteen eyes of eleven patients were studied. Preoperatively, the average axial length was 27.71±1.52 (25.56–30.80) mm, corneal diameter was 14.71±1.07 (13.0–16.0) mm, cup-to-disc ratio was 0.95±0.04 (0.9–1.0), and IOP was 39.5±5.7 (30–55) mmHg. The mean follow-up time was 18.29±10.96 (5–44, median 18) months. There were significant reductions in IOPs and the number of glaucoma medications (P<0.001) postoperatively. The IOPs after operation were 11.3±3.4, 13.6±5.1, 16.3±2.7, and 16.1±2.6 mmHg at 1 month, 6 months, 12?months, and 18 months, respectively. Kaplan–Meier estimates of the cumulative probability of valve success were 85.7%, 71.4%, and 71.4% at 6, 12, and 18 months, respectively. Severe surgical complications, including erosion of tube, endophthalmitis, retinal detachment, choroidal detachment, and delayed suprachoroidal hemorrhage, occurred in 28.6% cases.Conclusion: AGV implantation remains a viable option for patients with advanced primary congenital glaucoma unresponsive to previous surgical intervention, despite a relatively high incidence of severe surgical complications.
机译:目的:本研究的目的是评估7岁以下,先前手术失败的晚期原发性先天性青光眼患者的Ahmed青光眼瓣膜(AGV)植入术的中间患者。方法和方法:连续性晚期患者回顾性评估先前手术失败并随后进行了AGV植入的原发性先天性青光眼。手术成功的定义为:1)眼内压(IOP)≥6且≤21mmHg。 2)眼压相对于术前降低至少30%; 3)无需额外的手术干预来控制IOP,光感丧失或严重的并发症。结果:对11例患者的14眼进行了研究。术前平均轴向长度为27.71±1.52(25.56–30.80)mm,角膜直径为14.71±1.07(13.0-16.0)mm,杯碟比为0.95±0.04(0.9–1.0),IOP为39.5 ±5.7(30–55)毫米汞柱。平均随访时间为18.29±10.96(5–44,中位数18)个月。术后眼压和青光眼用药数量明显减少(P <0.001)。术后1个月,6个月,12个月和18个月的眼压分别为11.3±3.4、13.6±5.1、16.3±2.7和16.1±2.6 mmHg。 Kaplan–Meier估计在6、12和18个月时瓣膜成功的累积概率分别为85.7%,71.4%和71.4%。严重的外科手术并发症,包括输卵管糜烂,眼内炎,视网膜脱离,脉络膜脱离和脉络膜上膜迟发出血,发生率为28.6%。严重外科并发症的发生率相对较高。

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