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首页> 外文期刊>Clinical ophthalmology >Initiation and maintenance of a Treat-and-Extend regimen for ranibizumab therapy in wet age-related macular degeneration: recommendations from the UK Retinal Outcomes Group
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Initiation and maintenance of a Treat-and-Extend regimen for ranibizumab therapy in wet age-related macular degeneration: recommendations from the UK Retinal Outcomes Group

机译:在湿性年龄相关性黄斑变性中开始和维持雷珠单抗治疗的治疗扩展方案:来自英国视网膜结果小组的建议

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The treatment of neovascular (wet) age-related macular degeneration (AMD) with ranibizumab is now very well established in terms of efficacy and safety. Recent clinical trials and real-world studies have demonstrated the advantages of a Treat-and-Extend (T&E) regimen, and many hospital departments are now in the process of adopting this new regimen in favor of the pro re nata regimen for initiating and continuing ranibizumab therapy for patients with wet AMD. The comprehensive spectrum of issues related to implementation of the regimen is covered qualitatively in ten didactic topics provided by a group of clinicians with direct experience of this regimen in their department. The topics include definition, new and previously treated eyes, management of high-frequency injections, maximum extensions, discontinuing T&E, bilateral cases, clerical, audit, and patient counseling. This article aims to provide a useful resource for the implementation of the T&E regimen. A quantitative summary of the visual outcomes in key publications is also provided in this article. This article should be a valuable resource for staff training.
机译:就有效性和安全性而言,使用兰尼单抗治疗新血管性(湿性)年龄相关性黄斑变性(AMD)的方法现已非常成熟。最近的临床试验和现实世界研究已经证明了“扩展治疗”(T&E)方案的优势,许多医院部门现在都在采用这种新方案,以支持Pronata方案来启动和继续治疗。雷尼单抗治疗湿性AMD患者。与实施该方案有关的问题的综合范围在一组由直接在其部门中具有直接经验的临床医生提供的十个教学主题中进行了定性说明。主题包括定义,新的和先前治疗过的眼睛,高频注射的管理,最大扩展,终止T&E,双边病例,文书,审核和患者咨询。本文旨在为实施T&E方案提供有用的资源。本文还提供了主要出版物中视觉结果的定量摘要。本文应该是员工培训的宝贵资源。

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