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首页> 外文期刊>Clinical Pediatric Endocrinology >Treatment with GH in Three Patients with Intractable Nephrotic Syndrome and Severe Growth Failure
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Treatment with GH in Three Patients with Intractable Nephrotic Syndrome and Severe Growth Failure

机译：GH治疗三例顽固性肾病综合征和严重生长衰竭的患者

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Growth disorders induced by long term steroid hormone treatment are well known. We present here three cases of nephrotic syndrome treated with GH for severe short stature induced by long term steroid hormone therapy. Steroid hormone on alternate days (30 mg of predonisolone or 24 mg of methylpredonisolone) simultaneously for the treatment of three patients with nephrotic syndrome was necessary. Height growth before the beginning of the GH therapy was 1.5 cm, 3.0 cm and 2.6 cm per year. Height growth one year after the beginning of the GH therapy was 6.7 cm, 7.6 cm and 7.4 cm per year, respectively. Our data suggest that GH therapy is effective and safe for some cases of severe short stature patient with nephrotic syndrome.
机译：由长期类固醇激素治疗引起的生长障碍是众所周知的。我们在这里介绍了3例因长期类固醇激素治疗引起的严重身材矮小而接受GH治疗的肾病综合征。交替使用类固醇激素（泼尼松龙30 mg或甲基泼尼松龙24 mg）同时治疗3例肾病综合征的患者是必要的。 GH治疗开始之前的身高每年增长1.5厘米，3.0厘米和2.6厘米。 GH治疗开始后一年的身高增长分别为每年6.7 cm，7.6 cm和7.4 cm。我们的数据表明，GH治疗对于某些严重的身材矮小的肾病综合征患者是有效且安全的。

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