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首页> 外文期刊>Clinical medicine: journal of the Royal College of Physicians of London >Identifying antibiotic stewardship interventions to meet the NHS England CQUIN: an evaluation of antibiotic prescribing against published evidence-based antibiotic audit tools
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Identifying antibiotic stewardship interventions to meet the NHS England CQUIN: an evaluation of antibiotic prescribing against published evidence-based antibiotic audit tools

机译:确定符合英国NHS CQUIN标准的抗生素管理干预措施:根据已发布的循证抗生素审核工具对抗生素处方进行评估

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Evidence-based audit tools were used to identify the antibiotic stewardship improvements necessary to meet the NHS England targets in a 750-bed teaching hospital. Antibiotic prescribing was reviewed against published evidence-based audit tools for 139 patients treated with antibiotics. Severe community-acquired pneumonia (CAP) median course length was 8.5 days. Ninety-six percent of non-severe CAP patients were initiated on intravenous antibiotics (IV); median antibiotic course length 9 days. Twenty-six percent of urinary tract infection (UTI) patients without an indwelling catheter met the UTI diagnostic criteria. IV antibiotics initiated in 79% patients with other infections. Of these, 17% met the IV to oral switch criteria at 72 hours but were not switched. On average, antibiotic courses were 19% longer than recommended. Three key areas for improvement consist of: (a) implement the National Institute of Health and Care Excellence UTI Quality Standard - only 38% of patients treated for UTI met the UTI definition; (b) ensure antibiotic course lengths are in line with local prescribing guidelines - antibiotics were continued for 14% longer than recommended in local guidelines; (c) switch antibiotic therapy to oral when switch criteria met - 17% percent of patients initiated on IV antibiotics were eligible for oral switch by 72 hours and were not switched.
机译:基于证据的审计工具被用来确定必要的抗生素管理改进,以达到在拥有750张床的教学医院中达到NHS英格兰目标的目的。根据已发布的循证审核工具对139例接受抗生素治疗的患者进行了抗生素处方复查。严重的社区获得性肺炎(CAP)中位病程为8.5天。 96%的非严重CAP患者开始使用静脉注射抗生素(IV);中位抗生素疗程长9天。没有留置导管的尿路感染(UTI)患者中有26%符合UTI诊断标准。 79%的其他感染患者开始使用IV抗生素。其中,有17%的患者在72小时达到了从IV到口服的转换标准,但没有转换。平均而言,抗生素疗程比推荐时间长19%。需要改进的三个关键领域包括:(a)实施美国国立卫生研究院卓越的UTI质量标准-只有38%接受UTI治疗的患者符合UTI定义; (b)确保抗生素疗程的长度符合当地的处方指南-抗生素的使用时间比当地指南的建议长14%; (c)符合转换标准时将抗生素治疗改为口服-接受IV抗生素治疗的患者中有17%的患者有资格在72小时内进行口服转换,而未进行转换。

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