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首页> 外文期刊>Cogent Chemistry >Effect of drug Piper nigrum on physicochemical properties of zinc chloride at varying concentration and temperature investigated through ultrasonic tool
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Effect of drug Piper nigrum on physicochemical properties of zinc chloride at varying concentration and temperature investigated through ultrasonic tool

机译：通过超声工具研究了黑胡椒对不同浓度和温度下氯化锌的理化性质的影响

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In the present study, the molecular interaction between ethanolic extract of drug Piper nigrum with (metal ions) ZnCl_(2) have been investigated by ultrasonic method. The ultrasonic velocity (U ), density (ρ ), and viscosity (η ) of an ethanolic extract of drug with metal ions of different concentration (number of moles of drug?=?1.4018, 2.1027, 2.8036, and 3.5045) and different temperature (T?=?308.15, 313.15, 318.15, 323.15, and 333.15)?K at 2?MHz have been measured through ultrasonic interferometer. From experimental parameters (ultrasonic velocity (U ), density (ρ ) and viscosity (η )), various thermoacoustical parameters such as adiabatic compressibility (β ), intermolecular free length (L _(f )), specific acoustic impedance (Z ) has been calculated. The change in concentration of drug P. nigrum and varying temperature affects compressibility of solution, which gives idea about molecular interactions in liquid mixtures. Obtained experimental and thermoacoustical parameters are used to investigate the solute–solvent interactions between P. nigrum and ZnCl_(2) ions which is useful to understand the mechanism of their metabolism in living systems. The conclusion drawn from the ultrasonic investigation is the mixture act as structure breaker and there is a complex formation between ZnCl_(2) and P. nigrum for the system as a function of concentration and temperature. The results obtained from these studies are helpful for pharmacological applications of drugs, transport of drugs across biological membranes.
机译：在本研究中，通过超声方法研究了黑胡椒的乙醇提取物与（金属离子）ZnCl_（2）之间的分子相互作用。含金属离子浓度不同的药物的乙醇提取物的超声速度（iU），密度（iρ）和粘度（iη）（药物的摩尔数== 1.4018，2.1027 ，2.8036和3.5045）和不同的温度（T？=？308.15、313.15、318.15、323.15和333.15）？K是通过超声波干涉仪测量的。根据实验参数（超声速度（ U），密度（ρ）和粘度（η）），各种热声参数，例如绝热压缩率（β），分子间自由长度（ L _（ f）），已计算出比声阻抗（ Z）。药物P浓度的变化。黑液和变化的温度影响溶液的可压缩性，这使人们了解了液体混合物中的分子相互作用。获得的实验和热声参数用于研究P之间的溶质-溶剂相互作用。 Nigrum和ZnCl_（2）离子，对了解它们在生命系统中的代谢机理很有用。超声研究得出的结论是混合物充当结构破坏者，并且ZnCl_（2）和 P之间形成复杂的形成。系统的浓度是温度和浓度的函数。从这些研究中获得的结果有助于药物的药理学应用，药物跨生物膜的运输。

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