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Discrimination of Auditory Stimuli during Isoflurane Anesthesia

机译:异氟醚麻醉期间听觉刺激的区别

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Deepisofluraneanesthesiainitiatesaburstsuppressionpatterninwhichhigh-amplitudeburstsareprecededbyperiodsofnearlysilentelectroencephalogram.Theburstsuppressionratio(BSR)isthepercentageofsuppression(silentelectroencephalogram)duringtheburstsuppressionpatternandisoneparameterusedtoassessanesthesiadepth.Weinvestigatedcorticalburstactivityinratsinresponsetodifferentauditorystimulipresentedduringtheburstsuppressionstate.WenotedarapidappearanceofburstsandasignificantdecreaseintheBSRduringstimulation.TheBSRchangesweredistinctiveforthedifferentstimuliapplied,andtheBSRdecreasedsignificantlymorewhenstimulatedwithavoicefamiliartotheratascomparedwithanunfamiliarvoice.Theseresultsshowthatthecortexcanshowdifferentialsensoryresponsesduringdeepisofluraneanesthesia.
机译:Deepisofluraneanesthesiainitiatesaburstsuppressionpatterninwhichhigh-amplitudeburstsareprecededbyperiodsofnearlysilentelectroencephalogram.Theburstsuppressionratio(BSR)isthepercentageofsuppression(silentelectroencephalogram)duringtheburstsuppressionpatternandisoneparameterusedtoassessanesthesiadepth.Weinvestigatedcorticalburstactivityinratsinresponsetodifferentauditorystimulipresentedduringtheburstsuppressionstate.WenotedarapidappearanceofburstsandasignificantdecreaseintheBSRduringstimulation.TheBSRchangesweredistinctiveforthedifferentstimuliapplied,andtheBSRdecreasedsignificantlymorewhenstimulatedwithavoicefamiliartotheratascomparedwithanunfamiliarvoice.Theseresultsshowthatthecortexcanshowdifferentialsensoryresponsesduringdeepisofluraneanesthesia。

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