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Standardization Initiatives in the (eco)toxicogenomics Domain: A Review

机译:(生态)毒理基因组学领域的标准化举措:回顾

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The purpose of this document is to provide readers with a resource of different ongoingstandardization efforts within the ‘omics’ (genomic, proteomics, metabolomics)and related communities, with particular focus on toxicological and environmentalapplications. The review includes initiatives within the research community as well asin the regulatory arena. It addresses data management issues (format and reportingstructures for the exchange of information) and database interoperability, highlightingkey objectives, target audience and participants. A considerable amount of workstill needs to be done and, ideally, collaboration should be optimized and duplicationand incompatibility should be avoided where possible. The consequence of failing todeliver data standards is an escalation in the burden and cost of data managementtasks.
机译:本文档旨在为读者提供在“组学”(基因组学,蛋白质组学,代谢组学)和相关社区内正在进行的不同标准化工作的资源,尤其侧重于毒理学和环境应用。审查包括研究界以及监管领域的举措。它解决了数据管理问题(信息交换的格式和报告结构)和数据库互操作性,突出了关键目标,目标受众和参与者。需要完成大量工作,理想情况下,应该优化协作,并在可能的情况下避免重复和不兼容。无法交付数据标准的结果是,数据管理任务的负担和成本不断增加。

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