Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats

Zimberknopf Erica; Xavier Gilberto F; Kinsley Craig H; Felicio Luciano F

首页> 外文期刊>Comparative Medicine >Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats

【24h】

Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats

机译：先前的平价积极调节年轻和中年大鼠的学习和记忆

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Reproductiveexperienceinfemaleratsmodifiesacquiredbehaviors,induceslong-lastingfunctionalneuroadaptationsandcanalsomodifyspatiallearningandmemory.ThepresentstudysupportsandexpandsthisknowledgebasebyemployingtheMorriswatermaze,whichmeasuresspatialmemory.Age-matchedyoungadult(YNG)nulliparous(NULL;nonmated)andprimiparous(PRIM;onepregnancyandlactation)femaleratsweretested15dafterthelitter'sweaning.Inaddition,correspondingmiddle-aged(AGD)PRIM(matedinyoungadulthoodsothatpregnancy,parturition,andlactationoccurredatthesameageasinYNGPRIM)andNULLfemaleratsweretestedat18moofage.Behavioralevaluationincluded:1)acquisitionofreferencememory(platformlocationwasfixedfor14to19doftesting);2)retrievalofthisinformationassociatedwithextinctionoftheacquiredresponse(probetestinvolvingremovaloftheplatform24hafterthelasttrainingsession);and3)performanceinaworkingmemoryversionofthetask(platformpresentedinanovellocationeverydayfor13d,andmaintainedinafixedlocationwithineachday).YNGPRIMoutperformedNULLratsandshoweddifferentbehavioralstrategies.Theseresultsmayberelatedtochangesinlocomotor,mnemonic,andcognitiveprocesses.Inaddition,YNGPRIMexhibitedlessanxiety-likebehavior.ComparedwithYNGrats,AGDratsshowedlessbehavioralflexibilitybutstrongermemoryconsolidation.Thesedata,whichwereobtainedbyusingawell-documentedspatialtask,demonstratelonglastingmodificationsofbehavioralstrategiesinbothYNGandAGDratsassociatedwithasinglereproductiveexperience.

机译：Reproductiveexperienceinfemaleratsmodifiesacquiredbehaviors，induceslong-lastingfunctionalneuroadaptationsandcanalsomodifyspatiallearningandmemory.ThepresentstudysupportsandexpandsthisknowledgebasebyemployingtheMorriswatermaze，whichmeasuresspatialmemory.Age-matchedyoungadult（YNG）未经产的（NULL; nonmated）andprimiparous（PRIM; onepregnancyandlactation）femaleratsweretested15dafterthelitter'sweaning.Inaddition，correspondingmiddle老化（AGD）PRIM（matedinyoungadulthoodsothatpregnancy，分娩，andlactationoccurredatthesameageasinYNGPRIM）andNULLfemaleratsweretestedat18moofage。行为评估包括：1）获取参考内存（将平台位置固定为14到19d的测试）; 2）将该信息与获取的响应的灭绝相关联的检索（可能是在最后一次训练会话后的24小时内删除平台，并在整个工作日中将其保持不变，并且将所显示的工作日内的性能都保持不变，这表明该策略的有效期为3天）。 differentbehavioralstrategies.Theseresultsmayberelatedtochangesinlocomotor，记忆，andcognitiveprocesses.Inaddition，YNGPRIMexhibitedlessanxiety-likebehavior.ComparedwithYNGrats，AGDratsshowedlessbehavioralflexibilitybutstrongermemoryconsolidation.Thesedata，whichwereobtainedbyusingawell-documentedspatialtask，demonstratelonglastingmodificationsofbehavioralstrategiesinbothYNGandAGDratsassociatedwithasinglereproductiveexperience。

著录项

来源
《Comparative Medicine》 |2011年第4期|共页
作者
Zimberknopf Erica; Xavier Gilberto F; Kinsley Craig H; Felicio Luciano F;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类畜牧、动物医学、狩猎、蚕、蜂;
关键词

相似文献

外文文献
中文文献
专利

1. Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats [J] . Zimberknopf Erica (chucke@usp.br), Xavier Gilberto F., Kinsley Craig H., Comparative Medicine . 2011,第4期

机译：先前的平价积极调节年轻和中年大鼠的学习和记忆
2. Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry [J] . Sears James C., Choi Woong Jae, Broadie Kendal Neurobiology of disease . 2019,第期

机译：脆弱的X精神发育迟滞蛋白质呈正常调节PKA锚固rugose和PKA活动，以控制学习/存储器电路中的肌动蛋白组件
3. A comparison of learning and memory characteristics of young and middle-aged wild-type mice in the IntelliCage. [J] . Mechan AO, Wyss A, Rieger H, Journal of Neuroscience Methods . 2009,第1期

机译：IntelliCage中年轻和中年野生型小鼠的学习和记忆特征比较。
4. The effects of perinatal protein malnutrition on spatial learning and memory behaviour and brain-derived neurotrophic factor concentration in the brain tissue in young rats [C] . Ling Wang, Department of Food and Nutrition, Ruo-Jun Xu 国际营养科学联盟第八届临床营养学大会暨第五届亚太临床营养学会大会 . 2006

机译：围产期蛋白质营养不良对幼鼠脑组织空间学习记忆行为和脑源性神经营养因子浓度的影响
5. The influence of self-regulated learning and prior knowledge on knowledge acquisition in computer-based learning environments. [D] . Bernacki, Matthew. 2010

机译：自我调节的学习和先验知识对基于计算机的学习环境中的知识获取的影响。
6. Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats [O] . Erica Zimberknopf, Gilberto F Xavier, Craig H Kinsley, 2011

机译：先前的平价积极调节年轻和中年大鼠的学习和记忆
7. Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry [O] . James C. Sears, Woong Jae Choi, Kendal Broadie 2019

机译：脆弱的X精神迟发性蛋白质呈正常调节PKA锚固rugose和PKA活动，以控制学习/存储器电路中的肌动蛋白组件

Prior Parity Positively Regulates Learning and Memory in Young and Middle-Aged Rats

摘要

著录项

相似文献

相关主题

期刊订阅