Experimental Models of Peripheral Neuropathies

Notterpek Lucia; Tolwani Ravi J.

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Experimental Models of Peripheral Neuropathies

机译：周围神经病的实验模型

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BackgroundandPurpose:Peripheralneuropathies,disordersofperipheralnerves,resultfromgeneticalterationsorfrommetabolic,inflammatory,infectious,orchemicalinsults.Experimentalanimalmodels,spontaneousorinduced,existformanyofthecommonhumanperipheralneuropathies.Recentadvancesinhumangeneticshaveledtoidentificationofseveralspecificgenedefectsinvolvedinheritableneuropathiesandhaveallowedreproductionofthemoleculardefectsinexperimentalanimals.brxmlns="http://pub2web.metastore.ingenta.coms/"/brMethods:Geneticmodificationsinmiceandrats,similartothoseseeninhumans,alongwithanimalmodelsofspecificgenedefectsarepresentedanddiscussed.brxmlns="http://pub2web.metastore.ingenta.coms/"/brResultsandConclusion:Chemotherapeuticagentsadministeredtoaffectedanimalsmimicthedose-dependentneuropathiessimilartothoseseeninhumans.Availabilityoftheexperimentalanimalmodelshasbeeninvaluabletoanunderstandingofthepathogenesisofdiseaseandthedevelopmentofnewtreatments.

机译：BackgroundandPurpose：Peripheralneuropathies，disordersofperipheralnerves，resultfromgeneticalterationsorfrommetabolic，炎症，感染，orchemicalinsults.Experimentalanimalmodels，spontaneousorinduced，existformanyofthecommonhumanperipheralneuropathies.Recentadvancesinhumangeneticshaveledtoidentificationofseveralspecificgenedefectsinvolvedinheritableneuropathiesandhaveallowedreproductionofthemoleculardefectsinexperimentalanimals 方法：Geneticmodificationsinmiceandrats，结果与结论：化学治疗剂对人为模拟的可模仿动物的可食性的新病因在可食性动物模型中的发展是很有价值的。

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《Comparative Medicine》 |1999年第6期|共页
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Notterpek Lucia; Tolwani Ravi J.;
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中图分类畜牧、动物医学、狩猎、蚕、蜂;
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1. Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy [J] . Moustafa Passant E., Abdelkader Noha F., El Awdan Sally A., Inflammation . 2018,第4期

机译：实验性糖尿病周围神经病变中亚磺酸盐的细胞外基质重塑与炎症和氧化应激的调节
2. Experimental models of peripheral neuropathies [J] . Lucia Notterpek, Ravi J. Tolwani Laboratory Animal Science . 1999,第6期

机译：周围神经病的实验模型
3. Nonlinear Relation Between Burst Dorsal Root Ganglion Stimulation Amplitude and Behavioral Outcome in an Experimental Model of Painful Diabetic Peripheral Neuropathy [J] . Franken Glenn, Debets Jacques, Joosten Elbert A.J. Neuromodulation: journal of the International Neuromodulation Society . 2020,第2期

机译：脉冲背根神经节刺激振幅和疼痛性外周神经病变实验模型之间的非线性关系
4. Prediction of Diabetic Peripheral Neuropathy (DPN) using Plantar Pressure Analysis and Learning Models [C] . Ryan Rey A. Corpin, Hazel Anne R. Guingab, Adrian Nichol P. Manalo, International Conference on Humanoid, Nanotechnology, Information Technology, Communication and Control, Environment, and Management . 2019

机译：使用足底压力分析和学习模型预测糖尿病周围神经病变（DPN）
5. Microphysiological Model with Multiple Fiber Types for Modeling Diabetic Peripheral Neuropathy [D] . Watza, Keith. 2018

机译：多种纤维类型的微生理模型，用于糖尿病性周围神经病变的建模
6. Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy [O] . Chaoling Dong, E. Scott Helton, Ping Zhou, 2018

机译：在创伤性周围神经病的实验鼠模型中胶质细胞衍生的神经营养因子对于血液神经屏障功能恢复至关重要
7. Conventional Dorsal Root Ganglion Stimulation in an Experimental Model of Painful Diabetic Peripheral Neuropathy: A Quantitative Immunocytochemical Analysis of Intracellular γ‐Aminobutyric Acid in Dorsal Root Ganglion Neurons [O] . Glenn Franken, Perla Douven, Jacques Debets, 2021

机译：痛苦糖尿病周围神经病变实验模型中的常规背根神经节刺激：背根神经节细胞内γ-氨基丁酸的定量免疫细胞化学分析

Experimental Models of Peripheral Neuropathies

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