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ArraySearch: A Web-Based Genomic Search Engine

机译:ArraySearch:基于Web的基因组搜索引擎

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Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive.
机译:微阵列技术的最新进展导致了基因组学数据的泛滥。大量的累积数据可以用作帮助研究人员解释新实验数据的知识库。 ArraySearch发现新观察到的基因表达谱与公共领域保存的大量特征明确的表达签名之间的统计相关性。对基因列表的搜索查询将返回实验,在这些实验中,基因会明显上调或下调。也可以使用新实验中的基因表达签名进行搜索。该资源将使生物学研究人员能够采用统计方法,通过将其与大型公共档案馆中的表达签名进行比较来探索他们自己研究中的表达数据。

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