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首页> 外文期刊>Clinical & developmental immunology. >Determinants of Brachial-Ankle Pulse Wave Velocity in Chinese Patients with Rheumatoid Arthritis
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Determinants of Brachial-Ankle Pulse Wave Velocity in Chinese Patients with Rheumatoid Arthritis

机译：中国类风湿关节炎患者臂踝脉搏波速度的决定因素

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Objective . To investigate the relationship between Brachial-ankle pulse wave velocity (baPWV), and its associated risk factors in Chinese patients with RA. Methods . 138 Chinese RA patients and 150 healthy subjects were included. baPWV of all the participants was measured. RA related factors were determined, as well as traditional cardiovascular risk factors. Results . baPWV was significant higher in RA group (1705.44 ± 429.20?cm/s) compared to the healthy control group (1386.23 ± 411.09?cm/s) ( P < 0.001). Compared with low baPWV group, high baPWV group patients were significantly older ( P = 0.008) and taller ( P = 0.033). Serum cholesterol ( P = 0.035), triglycerides ( P = 0.004), and LDL level ( P = 0.006) were significantly higher in high baPWV group patients compared with low baPWV group patients. The baPWV of RA patients was positively correlated with age ( r = 0.439, P < 0.001), and serum cholesterol level ( r = 0.231, P = 0.035), serum triglycerides level ( r = 0.293, P < 0.001), serum LDL level ( r = 0.323, P = 0.003). Meanwhile, baPWV negatively correlated with the height of RA patients ( r = ?0.253, P = 0.043). Multivariate regression analysis showed that baPWV of RA group was independently associated with age and serum triglycerides level. Conclusions . The old age and high level of serum triglycerides may be the major determinants of arterial stiffness in Chinese RA patients.
机译：目标。目的探讨中国RA患者臂踝脉搏波速度（baPWV）与其相关危险因素的关系。方法 。包括138名中国RA患者和150名健康受试者。测量所有参与者的baPWV。确定了与RA相关的因素以及传统的心血管危险因素。结果。 RA组的baPWV（1705.44±429.20？cm / s）显着高于健康对照组（1386.23±411.09？cm / s）（P <0.001）。与低baPWV组相比，高baPWV组患者明显年龄更大（P = 0.008）和更高（P = 0.033）。高baPWV组患者的血清胆固醇（P = 0.035），甘油三酸酯（P = 0.004）和LDL水平（P = 0.006）显着高于低baPWV组患者。 RA患者的baPWV与年龄（r = 0.439，P <0.001），血清胆固醇水平（r = 0.231，P = 0.035），血清甘油三酸酯水平（r = 0.293，P <0.001），血清LDL水平呈正相关。 （r ＝ 0.323，P ＝ 0.003）。同时，baPWV与RA患者的身高呈负相关（r =±0.253，P = 0.043）。多元回归分析表明，RA组的baPWV与年龄和血清甘油三酯水平独立相关。结论。老年和高水平的血清甘油三酸酯可能是中国RA患者动脉僵硬的主要决定因素。

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