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Neonatal Sepsis due to Coagulase-Negative Staphylococci

机译：凝固酶阴性葡萄球菌引起的新生儿败血症

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Neonates, especially those born prematurely, are at high risk of morbidity and mortality from sepsis. Multiple factors, including prematurity, invasive life-saving medical interventions, and immaturity of the innate immune system, put these infants at greater risk of developing infection. Although advanced neonatal care enables us to save even the most preterm neonates, the very interventions sustaining those who are hospitalized concurrently expose them to serious infections due to common nosocomial pathogens, particularly coagulase-negative staphylococci bacteria (CoNS). Moreover, the health burden from infection in these infants remains unacceptably high despite continuing efforts. In this paper, we review the epidemiology, immunological risk factors, diagnosis, prevention, treatment, and outcomes of neonatal infection due to the predominant neonatal pathogen CoNS.
机译：新生儿，特别是早产儿，败血症的发病率和死亡率很高。多种因素，包括早产，侵入性救生医疗干预措施以及先天免疫系统的不成熟，使这些婴儿更容易发生感染。尽管先进的新生儿护理使我们甚至可以挽救最早产的新生儿，但维持住院者同时接受的干预措施却使他们由于常见的医院病原体，特别是凝固酶阴性葡萄球菌（CoNS），而受到严重感染。此外，尽管不断努力，这些婴儿的感染健康负担仍然很高。在本文中，我们回顾了主要由新生儿病原体CoNS引起的新生儿感染的流行病学，免疫危险因素，诊断，预防，治疗和结局。

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