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首页> 外文期刊>Comparative Medicine >Cardiovascular Pathology Possibly Associated with Ketamine/Xylazine Anesthesia in Dutch Belted Rabbits
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Cardiovascular Pathology Possibly Associated with Ketamine/Xylazine Anesthesia in Dutch Belted Rabbits

机译：荷兰腰带兔的氯胺酮/甲苯噻嗪麻醉可能与心血管病理相关

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BackgroundandPurpose:Aftermyocardialnecrosisandfibrosiswasobservedinfiverabbitswhichhadbeenanesthetizedavariablenumberoftimes,thepotentialrelationshipoftheselesionsandanesthesiawasevaluatedin35otherrabbits.brxmlns="http://pub2web.metastore.ingenta.coms/"/brMethods:AnesthesiawasinducedbyintramuscularadministrationofketamineandxylazinefollowedbyinfusionoflactatedRinger'ssolutionalsocontainingketamineandxylazine.GroupArabbits(n=9)weresubjectedtomultipleanesthesiasandwereevaluatedbyechocardiography,thoracicradiography,electrocardiography,determinationofserumcoronavirustiter,vitaminEconcentration,andcompletenecropsy.Priortoasingleacuteprocedurefollowedbynecropsy,groupBrabbits(n=11)wereevaluatedbyechocardiographyonly.GroupCrabbits(n=10)hadneverbeenanesthetizedandwerenecropsiedaftereuthanasia.GroupDrabbits(n=5)hadintermediateanesthesiaexposurehistoryandwereevaluatedbyechocardiographyonly.Myocardialfibrosiswasscoredsemi-quantitativelyonascaleof0to4.brxmlns="http://pub2web.metastore.ingenta.coms/"/brResults:Caninecoronavirustestresultswerenegative;hypovitaminosisEwasevident,andfibrosisscoresweresignificantlyincreasedingroupA,comparedwithgroupBorgroupC,rabbits.brxmlns="http://pub2web.metastore.ingenta.coms/"/brConclusion:Etiologicdifferentialsincluded#945;subxmlns="http://pub2web.metastore.ingenta.coms/"2/sub-agonist-mediatedcoronaryvasoconstrictionwithassociatedmyocardialhypoperfusion,hypovitaminosisEandfreeradicalinjury,andotheranesthetic-inducedphysiologictrespass.
机译：BackgroundandPurpose：Aftermyocardialnecrosisandfibrosiswasobservedinfiverabbitswhichhadbeenanesthetizedavariablenumberoftimes，thepotentialrelationshipoftheselesionsandanesthesiawasevaluatedin35otherrabbits 方法：AnesthesiawasinducedbyintramuscularadministrationofketamineandxylazinefollowedbyinfusionoflactatedRinger'ssolutionalsocontainingketamineandxylazine.GroupArabbits（N = 9）weresubjectedtomultipleanesthesiasandwereevaluatedbyechocardiography，thoracicradiography，心电图，determinationofserumcoronavirustiter， vitaminEconcentration，andcompletenecropsy.Priortoasingleacuteprocedurefollowedbynecropsy，groupBrabbits（N = 11）wereevaluatedbyechocardiographyonly.GroupCrabbits（N = 10）hadneverbeenanesthetizedandwerenecropsiedaftereuthanasia.GroupDrabbits（N = 5）hadintermediateanesthesiaexposurehistoryandwereevaluatedbyechocardiographyonly.Myocardialfibrosiswasscoredsemi-quantitativelyonascaleof0to4 结果：犬冠状病毒测试结果阴性;明显的低维生素血症和纤维化分数明显增加了groupgroupA，与groupBorgroupC，rabbits相比。包括病因学差异＃945; 2 -激动剂介导的冠状动脉血管狭窄伴有心肌灌注不足，维生素A缺乏症和自由基损伤，以及其他麻醉药诱发的生理侵入。

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