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首页> 外文期刊>Computational and Structural Biotechnology Journal >Evolutionary genomics and population structure of Entamoeba histolytica
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Evolutionary genomics and population structure of Entamoeba histolytica

机译：溶血变形虫的进化基因组学和种群结构

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Amoebiasis caused by the gastrointestinal parasite?Entamoeba histolytica?has diverse disease outcomes. Study of genome and evolution of this fascinating parasite will help us to understand the basis of its virulence and explain why, when and how it causes diseases. In this review, we have summarized current knowledge regarding evolutionary genomics of?E. histolytica?and discussed their association with parasite phenotypes and its differential pathogenic behavior. How genetic diversity reveals parasite population structure has also been discussed. Queries concerning their evolution and population structure which were required to be addressed have also been highlighted. This significantly large amount of genomic data will improve our knowledge about this pathogenic species of?Entamoeba.View HTML full text at: http://dx.doi.org/10.1016/j.csbj.2014.10.001
机译：胃肠道寄生虫引起的阿米巴病-溶组织阿米巴病具有多种疾病结局。对这种迷人的寄生虫的基因组和进化的研究将帮助我们了解其毒力的基础，并解释其为何，何时以及如何引起疾病。在这篇综述中，我们总结了有关？E进化基因组学的最新知识。组织蛋白酶，并讨论了它们与寄生虫表型的关系及其致病性差异。还讨论了遗传多样性如何揭示寄生虫种群结构。还强调了需要解决的有关其进化和人口结构的问题。大量的基因组数据将改善我们对这种Entamoeba致病物种的了解。查看HTML全文，网址为：http://dx.doi.org/10.1016/j.csbj.2014.10.001

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