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Induction of Fimbriated Vibrio cholerae O139

机译:纤维化霍乱弧菌O139的诱导

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Several fimbriated phases of Vibrio cholerae O139 strains were selectively induced and compared immunologically and biochemically with those of V. cholerae O1. Fimbrial antigens were detected on the surfaces of vibrio cells colonizing the epithelial cells of a rabbit small intestine. Convalescent-phase sera from six individuals infected with V. cholerae O139 revealed the development of antibody against the fimbrillin. These findings suggest that the fimbriae of V. cholerae O1 and O139 are expressed in vivo during infection and that consideration must be given to the use of fimbrial antigens as components of vaccines against cholera.
机译:选择性地诱导了霍乱弧菌O139菌株的几个纤维化阶段,并在免疫学和生化方面与 V进行了比较。霍乱 O1。在定殖于兔小肠上皮细胞的弧菌细胞表面检测到了纤维抗原。来自感染 V的六个人的恢复期血清。霍乱弧菌O139揭示了抗纤颤蛋白抗体的发展。这些发现表明 V的菌毛。霍乱杆菌O1和O139在感染期间在体内表达,必须考虑使用纤维抗原作为霍乱疫苗的成分。

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