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首页> 外文期刊>Clinical and diagnostic laboratory immunology >Duration of Sample Storage Dramatically Alters Expression of the Human Immunodeficiency Virus Coreceptors CXCR4 and CCR5
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Duration of Sample Storage Dramatically Alters Expression of the Human Immunodeficiency Virus Coreceptors CXCR4 and CCR5

机译:样品存储的持续时间显着改变了人类免疫缺陷病毒共受体CXCR4和CCR5的表达

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Expression of the chemokine receptors CXCR4 and CCR5 was monitored using EDTA-anticoagulated whole blood held for different time periods prior to fluorescent-antibody staining. When left overnight CXCR4 expression on leukocytes was substantially increased, whereas CCR5 expression was reduced. The results were similar when heparin and acid-citrate-dextrose were used as anticoagulants.
机译:在荧光抗体染色之前,使用在不同时间段保持的EDTA抗凝全血监测趋化因子受体CXCR4和CCR5的表达。当放置过夜时,白细胞上的CXCR4表达显着增加,而CCR5表达降低。当使用肝素和柠檬酸右旋糖作为抗凝剂时,结果相似。

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