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首页> 外文期刊>Clinical and diagnostic laboratory immunology >Determination of varicella-zoster virus (VZV) immune status with the VIDAS VZV immunoglobulin G automated immunoassay and the VZVScan latex agglutination assay.
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Determination of varicella-zoster virus (VZV) immune status with the VIDAS VZV immunoglobulin G automated immunoassay and the VZVScan latex agglutination assay.

机译：使用VIDAS VZV免疫球蛋白G自动免疫测定法和VZVScan乳胶凝集测定法确定水痘带状疱疹病毒（VZV）的免疫状态。

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摘要

The VIDAS varicella-zoster virus (VZV) immunoglobulin G immunoassay and the VZVScan latex agglutination (LA) test were compared for the detection of VZV antibody in patient sera. Of 625 samples tested, 554 were positive for VZV antibody by one or both methods. Five hundred thirteen (82.1%) samples were positive by both methods, 71 (11.4%) were negative by both methods, and there were 41 (6.6%) discrepant samples. Statistically significant differences in sensitivity and specificity were not found (P = 0.37); however, several observations were made. All 23 VIDAS repeat equivocal samples were LA positive. Fifty-four samples showed prozone effects with the LA assay, all of which resolved as positive.
机译：比较了VIDAS水痘带状疱疹病毒（VZV）免疫球蛋白G免疫测定法和VZVScan乳胶凝集（LA）测试，以检测患者血清中的VZV抗体。在一种或两种方法中，在625个样本中，有554个VZV抗体呈阳性。两种方法均检出513份（82.1％）阳性，两种方法均检出71份（11.4％）阴性，差异41份（6.6％）。在敏感性和特异性上未发现统计学上的显着差异（P = 0.37）;但是，进行了一些观察。所有23个VIDAS重复模棱两可的样本均为LA阳性。 54个样品在LA分析中显示出前带区效应，所有这些均被解析为阳性。

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