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首页> 外文期刊>Critical Care Research and Practice >Contemporary Trends of the Epidemiology, Clinical Characteristics, and Resource Utilization of Necrotizing Fasciitis in Texas: A Population-Based Cohort Study
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Contemporary Trends of the Epidemiology, Clinical Characteristics, and Resource Utilization of Necrotizing Fasciitis in Texas: A Population-Based Cohort Study

机译：德克萨斯州坏死性筋膜炎的流行病学，临床特征和资源利用的当代趋势：基于人群的队列研究

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Introduction. There are limited population-level reports on the contemporary trends of the epidemiology, clinical features, resource utilization, and outcomes of necrotizing fasciitis (NF).Methods. We conducted a cohort study of Texas inpatient population, identifying hospitalizations with a diagnosis of NF during the years 2001–2010. The incidence, clinical features, resource utilization, and outcomes of NF hospitalizations were examined.Results. There were 12,172 NF hospitalizations during study period, with ICU admission in 50.3%. The incidence of NF rose 2.7%/year (P=0.0001). Key changes between 2001-2002 and 2009-2010 included rising incidence of NF (5.9 versus 7.6 per 100,000 [P<0.0001]), chronic comorbidities (69.4% versus 76.7% [P<0.0001]), and development of ≥1 organ failure (28.5% versus 51.7% [P<0.0001]). Inflation-adjusted hospital charges rose 37% (P<0.0001). Hospital mortality (9.3%) remained unchanged during study period. Discharges to long-term care facilities rose from 12.2 to 30% (P<0.0001).Conclusions. The present cohort of NF is the largest reported to date. There has been increasing incidence, chronic illness, and severity of illness of NF over the past decade, with half of NF hospitalizations admitted to ICU. Hospital mortality remained unchanged, while need for long-term care rose nearly 2.5-fold among survivors, suggesting increasing residual morbidity. The sources of the observed findings require further study.
机译：介绍。关于当代流行病学趋势，临床特征，资源利用以及坏死性筋膜炎（NF）结局的报告，在人群水平上报道有限。我们对德克萨斯州住院患者进行了队列研究，确定了2001-2010年间诊断为NF的住院患者。检查了NF住院的发生率，临床特征，资源利用和结局。在研究期间，有12172例NF住院，其中ICU入院率为50.3％。 NF的发生率/年上升了2.7％（P = 0.0001）。 2001-2002年和2009-2010年之间的主要变化包括NF发生率上升（每100,000发生5.9对7.6 [P <0.0001]），慢性合并症（69.4％对76.7％[P <0.0001]）以及器官衰竭≥1的发生（28.5％对51.7％[P <0.0001]）。经通货膨胀调整后的医院费用上升了37％（P <0.0001）。在研究期间，医院死亡率（9.3％）保持不变。长期护理设施的出院率从12.2％上升至30％（P <0.0001）。当前的NF队列是迄今为止报道的最大队列。在过去的十年中，NF的发病率，慢性病和疾病的严重程度不断增加，一半的NF住院治疗被送入ICU。医院死亡率保持不变，而幸存者中需要长期护理的人数增长了近2.5倍，这表明残存病率正在增加。观察到的结果的来源需要进一步研究。

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