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首页> 外文期刊>Acta Cirurgica Brasileira >Mycobacterium massiliense BRA100 strain recovered from postsurgical infections: resistance to high concentrations of glutaraldehyde and alternative solutions for high level disinfection
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Mycobacterium massiliense BRA100 strain recovered from postsurgical infections: resistance to high concentrations of glutaraldehyde and alternative solutions for high level disinfection

机译：从术后感染中恢复的马氏分枝杆菌BRA100菌株：对高浓度戊二醛和高浓度消毒的替代解决方案具有抵抗力

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PURPOSE: To evaluate the minimum inhibitory concentration (MIC) of GTA against these microorganisms and alternative disinfectants for high-level disinfection (HLD). METHODS: Reference mycobacteria and clinical M. massiliense strains were included in this study. Active cultures were submitted to susceptibility qualitative tests with GTA dilutions (ranging from 1.5% to 8%), and commercial orthophthaldehyde (OPA) and peracetic acid (PA) - based solutions, during the period of exposure as recommended by National Agency of Sanitary Surveillance for HLD. RESULTS: All reference and M. massiliense non-BRA100 strains, recovered from sputum, were susceptible to any GTA concentration, OPA and PA solutions. M. massiliense BRA100 strains presented MIC of 8% GTA and were susceptible to OPA and PA. CONCLUSION: M. massiliense BRA100 strain is resistant to high GTA concentrations (up to 7%), which proves that this product is non-effective against specific rapidly growing mycobacteria and should be substituted by OPA or PA - based solutions for HLD.
机译：目的：评估对这些微生物和高水平消毒（HLD）的替代消​​毒剂的GTA最低抑制浓度（MIC）。方法：本研究包括参考分枝杆菌和临床M. massiliense菌株。根据国家卫生监督局的建议，在暴露期间，将活性培养物进行GTA稀释度（范围为1.5％至8％）以及市售邻苯二甲醛（OPA）和过氧乙酸（PA）的溶液的敏感性定性测试。用于HLD。结果：从痰液中回收的所有参考菌株和M. massiliense非BRA100菌株均对任何GTA浓度，OPA和PA溶液敏感。 M. massiliense BRA100菌株的MIC为8％GTA，对OPA和PA敏感。结论：M。massiliense BRA100菌株对高GTA浓度（高达7％）具有抗性，这证明该产品对快速增长的特定分枝杆菌无效，应使用基于OPA或PA的溶液替代HLD。

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