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首页> 外文期刊>Advanced Biomedical Research >A comparison of two interventions for HHHFNC in preterm infants weighing 1,000 to 1,500 g in the recovery period of newborn RDS
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A comparison of two interventions for HHHFNC in preterm infants weighing 1,000 to 1,500 g in the recovery period of newborn RDS

机译：在新生儿RDS康复期对体重在1,000至1,500 g的早产儿进行HHHFNC的两种干预措施的比较

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Background: Nasal cannula, beside administering low-flow therapy, showed the capability for the administration of continuous positive airway pressure (CPAP) through high-flow nasal cannula (HFNC). Meeting specific physical criteria of 100% relative humidity (RH) and temperature of 37 o C are the basic interventional requirements to administer oxygen for the newborns through a nasal cannula. Recently, two systems, MR850 and PMH7000, received the Food and Drug Administration (FDA) approval to administer heated, humidified HFNC (HHHFNC). These systems are evaluated in this study based on their humidifying and heating capabilities. Materials and Methods: This study was done as an RCT on newborns weighing 1,000 to 1,500 g recovering from respiratory distress syndrome (RDS) while nCPAP was administered at CDP = 4 cmH 2 O, Fio 2 Results: The average time of support with HHHNFC did not show any significant difference in the two groups. There was no significant difference between the groups in the need for nCPAP, invasive ventilation, apnea, nasal trauma, and CLD. The difference in the levels of average temperature and humidity was significant ( P value Conclusion: Although the records of temperature and RH in the PMH7000 system was lower than the records from the MR850 system, no clinical priority was observed for respiratory support with HHHNFC in the two systems.
机译：背景：鼻插管除了进行低流量治疗外，还具有通过高流量鼻插管（HFNC）持续施加持续气道正压（CPAP）的能力。满足通过鼻插管为新生儿提供氧气的基本干预要求，即达到100％相对湿度（RH）和温度为37°C C的特定物理标准。最近，两个系统MR850和PMH7000已获得美国食品药品监督管理局（FDA）的批准，用于管理加热加湿的HFNC（HHHFNC）。这些研究根据其加湿和加热能力对其进行了评估。材料和方法：本研究以RCT方式进行，研究对象是从呼吸窘迫综合征（RDS）中康复的体重在1,000至1,500 g的新生儿，而nCPAP的给药剂量为CDP = 4 cmH 2 O，Fio 2 结果：HHHNFC的平均支持时间在两组中没有显着差异。两组之间在nCPAP，有创通气，呼吸暂停，鼻外伤和CLD方面的需求无显着差异。平均温度和湿度水平之间的差异非常显着（P值结论：尽管PMH7000系统中的温度和相对湿度记录低于MR850系统中的相对湿度记录，但在HHHNFC中，对HHHNFC的呼吸支持并没有临床优先考虑两个系统。

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