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Medical Management of Brain-Dead Organ Donors

机译:脑死亡器官捐献者的医疗管理

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With improving healthcare services, the demand for organ transplants has been increasing daily worldwide. Deceased organ donors serve as a good alternative option to meet this demand. The first step in this process is identifying potential organ donors. Specifically, brain-dead patients require aggressive and intensive care from the declaration of brain death until organ retrieval. Currently, there are no specific protocols in place for this, and there are notable variations in the management strategies implemented across different transplant centers. Some transplant centers follow their own treatment protocols, whereas other countries, such as Bangladesh, do not have any protocols for potential organ donor care. In this review, we discuss how to identify brain-dead donors and describe the physiological changes that occur following brain death. We then summarize the management of brain-dead organ donors and, on the basis of a review of the literature, we propose recommendations for a treatment protocol to be developed in the future.
机译:随着医疗服务的改善,全球器官移植的需求每天都在增加。死者的器官捐献者是满足此需求的不错选择。此过程的第一步是确定潜在的器官捐献者。具体而言,脑死亡患者从宣布脑死亡到器官恢复,都需要积极和深入的护理。当前,没有针对此的特定协议,并且跨不同移植中心实施的管理策略也存在显着差异。一些移植中心遵循自己的治疗方案,而其他国家(例如孟加拉国)没有任何潜在的器官捐赠者护理方案。在这篇综述中,我们讨论了如何识别脑死亡的供体并描述了脑死亡后发生的生理变化。然后,我们总结了脑死亡器官捐献者的管理方式,并在回顾文献的基础上,提出了有关未来开发治疗方案的建议。

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