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首页> 外文期刊>Acute and critical care. >Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest
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Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest

机译：院外心脏骤停后心跳骤停综合征患者短期死亡率与中度至重度左心室射血分数

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Background The aim of this study was to investigate the relationships between left ventricular ejection fraction (LVEF) and mortality and neurologic outcomes with post-cardiac arrest syndrome (PCAS) after out-of-hospital cardiac arrest (OHCA). Methods Patients with PCAS after OHCA admitted to the intensive care unit between January 2014 and December 2015 were analyzed retrospectively. Results A total of 104 patients were enrolled in this study. The mean age was 54.4 ± 15.3 years, and 75 of the patients were male (72.1%). Arrest with a cardiac origin was found in 55 (52.9%). LVEF 55% was measured in 39 (37.5%), 18 (17.3%), and 47 (45.2%) of patients, respectively. In multivariate analysis, severe LV dysfunction (LVEF 45%) was significantly related to 7-day mortality (odds ratio 3.02, 95% Confidence Interval 1.01-9.0, p-value 0.047). Conclusions In this study, moderate to severe LVEF within 48 hours after return of spontaneous circulation was significantly related to 7-day short-term mortality in patients with PCAS after OHCA. Clinicians should actively treat myocardial dysfunction, and further studies are needed.
机译：背景技术这项研究的目的是调查院外心脏骤停（OHCA）后左心室射血分数（LVEF）与死亡率和心律失常后综合征（PCAS）的神经系统结局之间的关系。方法回顾性分析2014年1月至2015年12月OHCA入院的PCAS患者。结果本研究共纳入104例患者。平均年龄为54.4±15.3岁，其中75例患者为男性（72.1％）。发现有心脏起搏的人为55（52.9％）。 LVEF 55％分别在39（37.5％），18（17.3％）和47（45.2％）的患者中测得。在多变量分析中，严重的左室功能不全（LVEF <45％）与7天死亡率显着相关（比值3.02，95％置信区间1.01-9.0，p值0.047）。结论在本研究中，自发性循环恢复后48小时内中度至重度LVEF与OHCA后PCAS患者7天短期死亡率显着相关。临床医生应积极治疗心肌功能障碍，需要进一步研究。

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