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Epidemiological Characteristics Based on the Underlying Diseases for the Deaths Related to Pandemic H1N1 Influenza in Korea

机译:基于与大流行H1N1流感有关的死亡的潜在疾病的流行病学特征

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BACKGROUND: Since May 2009, a pandemic influenza A (H1N1) virus has emerged and spread nationwide. We describe the epidemiological characteristics of the confirmed deaths related with the 2009 H1N1 influenza pandemic in Korea from May 2009 to mid December 2009. METHODS: This study was based on an analysis of the reports from the deaths of confirmed cases pandemic H1N1 virus until 7 December 2009 in Korea. These reports were compiled by the epidemic intelligence team at the Korea Centers for Disease Control & Prevention (KCDC) or at the provinces. The epidemic intelligence team used an identical, well-defined investigate form for reviewing the medical records and for interviewing the physicians in charge of the cases. RESULTS: The first confirmed death occurred on August 15, 2009. Until December 7, 2009, 139 deaths had been reported. Eighty cases (57.6%) were individuals more than 60 years old. Sixty two cases (47.0%) were dead within 7 days from the onset of symptoms. One hundred three cases (74%) had underlying diseases, and cancer was the most common underlying disease. The proportion of patients using antivial medications before confirmation among the patients with underlying diseases was greater than the proportion of patients using antivial medications among the patients with no underlying diseases. CONCLUSIONS: During the evaluation period, serious underlying diseases were present in nearly three quarters of the cases of confirmed death. We suggest that health providers consider using antiviral drugs before confirmation of pandemic H1N1 in hospitalized patients, and especially in those with underlying diseases.
机译:背景:自2009年5月以来,甲型H1N1大流行性流感病毒已经出现并在全国传播。我们描述了2009年5月至2009年12月中旬在韩国与2009 H1N1流感大流行相关的已确诊死亡的流行病学特征。方法:本研究基于对直至12月7日的H1N1大流行确诊病例死亡报告的分析。 2009年在韩国。这些报告是由韩国疾病控制与预防中心(KCDC)或各省的流行情报团队编写的。流行病情报小组使用了一种相同的,定义明确的调查表,以检查病历并采访负责此案的医生。结果:首次确认的死亡发生在2009年8月15日。到2009年12月7日,已经报告了139例死亡。年龄在60岁以上的个体有80例(57.6%)。症状发作后7天内有62例(47.0%)死亡。一百零三例(74%)患有基础疾病,而癌症是最常见的基础疾病。在患有基础疾病的患者中,在确认之前使用抗病毒药物的患者比例大于没有基础疾病的患者中使用抗病毒药物的患者比例。结论:在评估期间,近四分之三的确诊死亡病例中存在严重的基础疾病。我们建议健康提供者在住院患者,尤其是患有基础疾病的患者中确认大流行H1N1之前考虑使用抗病毒药物。

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