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首页> 外文期刊>Acute Medicine & Surgery >Comparative analysis of mamushi (Gloydius blomhoffii) bite patients indicates that creatinine kinase levels/white blood cell count trends reflect severity
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Comparative analysis of mamushi (Gloydius blomhoffii) bite patients indicates that creatinine kinase levels/white blood cell count trends reflect severity

机译：对mamushi（ G loydius blomhoffii ）咬伤患者的比较分析表明，肌酐激酶水平/白细胞计数趋势反映了严重程度

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Aim There has been no indicator that allows an early quantitative evaluation of the severity of a mamushi snake ( G loydius blomhoffii ) bite. Because the number of severe mamushi bite cases is much fewer than non‐severe cases, a formal case–control study is difficult. Therefore, we tried to generate a preliminary quantitative, real‐time index for its severity by referring to published reports of severe mamushi bite cases. Methods We enrolled patients who presented with a mamushi bite and visited our outpatient clinic. Severe cases were collected from published works. Creatinine kinase levels and white blood cell counts of non‐severe and severe cases were compared and analyzed. Results There was a lag time of 10?h before the creatinine kinase level began to rise. The speed of the increase was higher in severe cases than in non‐severe cases, and severe cases were recognized as those showing speeds of above 250? IU /L/h. White blood cell counts increased earlier than creatinine kinase levels without any lag time. Severe cases were recognized as those with the counts of over 1,000?×?(h)?+?6,000 [/μL] before 5?h and 300?×?(h)?+?10,000 [/μL] after 5?h. Conclusion We herein present the creatinine kinase level and white blood cell count trends and demonstrate preliminary cut‐off equations. The trends for both parameters serve as quantitative indicators of the severity of a mamushi bite until a large scale case–control study is achieved.
机译：目的目前尚无指标可早期定量评估猛m蛇咬伤的严重程度。由于严重的mamushi叮咬病例的数量要比非严重的病例少得多，因此很难进行正式的病例对照研究。因此，我们试图参考已发表的严重mamushi咬伤病例报告，为其严重程度建立初步的定量实时指标。方法我们招募了被猛禽咬伤并去门诊就诊的患者。从已发表的作品中收集了严重的案例。比较和分析了非严重和严重病例的肌酐激酶水平和白细胞计数。结果肌酐激酶水平开始升高之前有10？h的滞后时间。严重情况下的增加速度高于非严重情况下的增加速度，并且严重情况被认为是显示速度超过250？单位/升/小时白细胞计数比肌酐激酶水平增加得更早，没有任何滞后时间。严重者被认为是在5小时之前的计数超过1,000？×？（h）？+？6,000 [/μL]的病例，在5小时之后计数超过300？×？（h）？+？10,000 [/μL]的病例。 。结论我们在此介绍了肌酸酐激酶水平和白细胞计数趋势，并演示了初步的截止方程。在完成大规模病例对照研究之前，这两个参数的趋势可作为定量检测猛禽叮咬严重程度的指标。

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