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Anti‐NMDAR encephalitis: case report and diagnostic issues

机译: NMDAR 脑炎:病例报告和诊断问题

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Case A 20‐year‐old woman developed acute psychotic symptoms and altered level of consciousness. She presented with neck stiffness, tremulous arms, facial dyskinesia, and distension of the lower abdomen. Pelvic magnetic resonance imaging showed bilateral ovarian teratomas. Anti‐ N ‐methyl‐ D ‐aspartate receptor antibodies were detected in her cerebrospinal fluid. Outcome Resection of the tumors and immunotherapy were carried out. She gradually recovered and was discharged with few neurological deficits on the 105th day of hospitalization. Conclusion Our survey of 63 previous reports describing 92 cases revealed that 21.7% of the patients were sent to emergency departments and 59.8% of the patients were managed in intensive care units. Emergency physicians and intensivists should be aware of this disorder, as they may encounter undiagnosed disorders in patients with epileptic attacks, acute psychotic signs, dyskinesia, or hypoventilation in the course of the illness.
机译:案例一名20岁女性出现了急性精神病症状并改变了意识水平。她表现出脖子僵硬,手臂颤抖,面部运动障碍和小腹胀大。骨盆磁共振成像显示双侧卵巢畸胎瘤。在她的脑脊液中检测到抗N-甲基-D-天冬氨酸受体抗体。结果切除肿瘤并进行免疫治疗。她逐渐康复并在住院的第105天出院,几乎没有神经功能缺损。结论我们对之前的63份报道(共92例病例)进行的调查显示,有21.7%的患者被送往急诊科,而59.8%的患者被送往重症监护室。急诊医师和强化医生应注意这种疾病,因为在病程中患有癫痫发作,急性精神病征,运动障碍或通气不足的患者可能会遇到无法诊断的疾病。

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