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首页> 外文期刊>Acute Medicine & Surgery >Mild manifestation of methanol poisoning half a day after massive ingestion of a fuel alcohol product containing 70% ethanol and 30% methanol: a case report
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Mild manifestation of methanol poisoning half a day after massive ingestion of a fuel alcohol product containing 70% ethanol and 30% methanol: a case report

机译：大量摄入含有70％乙醇和30％甲醇的燃料酒精产品半天后，甲醇中毒的轻微表现：一例

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Case Is fomepizole necessary after massive ingestion of a mixture of methanol and ethanol? We report the case of a 37‐year‐old man who was transported to our Poison Center 12?h after ingesting 500?mL of fuel alcohol containing 70% methanol and 30% ethanol in a suicide attempt. On admission, he presented only with somnolence and mild metabolic acidosis. We hypothesized that most of the ethanol had been metabolized. Outcome As the estimated serum concentration of methanol was lethal (242.6?mg/dL), fomepizole was given i.v. and hemodialysis was carried out twice, resulting in complete recovery. Later, the serum concentrations of both methanol and ethanol on admission were found to be 224.1 and 0.51?mg/ dL , respectively. Conclusion Therapeutic intervention was delayed by half a day after ingestion of a product containing methanol and ethanol in the present case. If the patient had arrived earlier, he may have only been treated with hemodialysis, but not fomepizole. A 37‐year‐old man was transported to our Poison Center 12?h after ingesting 500?mL of fuel alcohol containing 70% methanol and 30% ethanol, presenting only with somnolence and mild metabolic acidosis. He was successfully treated with fomepizole and hemodialysis. Later, the serum concentration of methanol on admission was found to be lethal (224.1?mg/dL), but the amount of ethanol was small (0.51?mg/dL). We concluded that the patient may have only been treated with hemodialysis, but not fomepizole, if he had arrived earlier.
机译：病例大量摄入甲醇和乙醇的混合物后是否有必要使用甲吡咪唑？我们报告了一个案例，该案例是一名37岁的男子在自杀尝试中摄入500？mL含70％甲醇和30％乙醇的燃料酒精后12小时被运送到我们的毒物中心。入院时，他仅表现出嗜睡和轻度代谢性酸中毒。我们假设大多数乙醇已被代谢。结果由于估计的甲醇血清浓度具有致死性（242.6？mg / dL），因此静脉注射氟吡哌唑。进行两次血液透析，完全康复。后来，入院时甲醇和乙醇的血清浓度分别为224.1和0.51？mg / dL。结论在本例中，摄入含甲醇和乙醇的产品后，治疗干预延迟了半天。如果患者较早到达，则可能仅接受了血液透析治疗，而未接受甲吡咪唑治疗。一名37岁的男子在摄入500？mL含70％甲醇和30％乙醇的燃料酒精后12小时被运送到我们的毒物中心，仅表现为嗜睡和轻度的代谢性酸中毒。他成功地接受了fomepizole和血液透析治疗。后来，发现入院时甲醇的血清浓度具有致命性（224.1？mg / dL），但乙醇的量很少（0.51？mg / dL）。我们得出的结论是，如果患者较早到达，则可能仅接受了血液透析治疗，而未接受甲吡咪唑治疗。

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