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首页> 外文期刊>Acute and critical care. >Severe Fever with Thrombocytopenia Syndrome
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Severe Fever with Thrombocytopenia Syndrome

机译：严重发热伴血小板减少综合征

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Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging infectious disease, caused by a novel species of Phlebovirus of Bunyaviridae family, in China, South Korea, and Japan. SFTS is primarily known as a tick-borne disease, and human-to-human transmission is also possible in contact with infectious blood. Common clinical manifestations include fever, thrombocytopenia, and leukopenia as initial symptoms, and multiple organ dysfunction and failure manifest with disease progression. Whereas disease mortality is reported to be 12% to 30% in China, a recent report of cumulative SFTS cases indicated 47% in Korea. Risk factors associated with SFTS were age, presence of neurologic disturbance, serum enzyme levels, and elevated concentrations of certain cytokines. Diagnosis of SFTS is based on viral isolation, viral identification by polymerase chain reaction, and serologic identification of specific immunoglobulin G. Therapeutic guideline has not been formulated, but conservative management is the mainstream of treatment to prevent disease progression and fatal complications.
机译：患有血小板减少症候群（SFTS）的重度发烧是一种新出现的传染病，由中国，韩国和日本的Bunyaviridae家族的一种新型静脉病毒引起。 SFTS主要被称为壁虱传播的疾病，与传染性血液接触时人与人之间的传播也是可能的。常见的临床表现包括发烧，血小板减少和白细胞减少作为初始症状，多器官功能障碍和衰竭随着疾病的发展而显现。据报道，中国的疾病死亡率为12％至30％，而最近的累积SFTS病例报告显示，韩国为47％。与SFTS相关的危险因素是年龄，神经功能障碍的存在，血清酶水平以及某些细胞因子的浓度升高。 SFTS的诊断基于病毒分离，通过聚合酶链反应进行病毒鉴定以及特异性免疫球蛋白G的血清学鉴定。治疗指南尚未制定，但保守治疗是预防疾病进展和致命并发症的主流治疗方法。

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