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首页> 外文期刊>Advances in Life Sciences >Study of Multiple-Drug Resistance Transfer Factors from Isolated E. coli of Poultry Farms to Salmonella typhimurium
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Study of Multiple-Drug Resistance Transfer Factors from Isolated E. coli of Poultry Farms to Salmonella typhimurium

机译：从分离的 E中研究多重耐药性转移 因子 的研究。家禽场的大肠杆菌对沙门氏菌鼠伤寒

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Different studies on animals in around the world show that there are multiple-drug resistance in strains of Escherichia coli (E. coli ). Such microorganisms are notorious for the extension of colibacillosis in poultry, which great economic losses bring for the poultry industry. This study was carried out to determine drug resistance and resistance factor transfer in E. coli strains isolated from poultry farms, in south west of Iran. Than 100 pieces of poultry carcasses from cases of colibacilosis twenty-five E. coli resistant to one or more antibiotics were isolated and were analyzed to determine their drug resistance pattern and also transfer of resistance factor via conjugation. The highest rate of resistance was against nalidixic acid and tetracycline. Multiple drug resistance was shown in 80% of strains. By using Salmonella typhimurium RITCC1730 (S. typhimurium ) as a recipient and E. coli as donor’s resistance factor examined the transfer of drug resistance that the highest rate of transfer was related to neomycin and tiamulin 68% and 64%, respectively.Finally, we concluded that there are a substantially evidence of multiple drug resistance in E. coli isolates taken from poultry farms, so in our opinion restricting use of antibiotics and performing antimicrobial susceptibility tests to select suitable antibiotic can decrease developing of resistant strains.
机译：全世界对动物的不同研究表明，大肠杆菌（i。coli）菌株具有多重耐药性。这种微生物以禽类中的大肠杆菌病的传播而臭名昭著，这给家禽业带来了巨大的经济损失。进行这项研究以确定E中的耐药性和耐药因子转移。从伊朗西南部的家禽养殖场分离出的大肠杆菌菌株。从25例大肠杆菌中检出100多个家禽屠体。分离出对一种或多种抗生素具有抗性的大肠埃希菌，并进行分析以确定它们的耐药模式，以及通过结合转移耐药因子。耐药率最高的是萘啶酸和四环素。在80％的菌株中显示出多重耐药性。通过使用鼠伤寒沙门氏菌RITCC1730（鼠伤寒沙门氏菌）作为受体和大肠杆菌。大肠杆菌作为供体的抗性因子检查了耐药性的转移，转移的最高速率分别与新霉素和头菌素有关，分别为68％和64％。最后，我们得出结论，基本上有证据表明 E具有多重耐药性。从家禽养殖场中提取的大肠埃希菌，因此在我们看来，限制使用抗生素并进行抗菌药敏试验以选择合适的抗生素可以减少耐药菌株的产生。

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