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首页> 外文期刊>Addiction Science & Clinical Practice >Testing for amphetamine-type stimulant (ATS) use to ascertain validity of self-reported ATS use among young female sex workers in Cambodia
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Testing for amphetamine-type stimulant (ATS) use to ascertain validity of self-reported ATS use among young female sex workers in Cambodia

机译:测试苯丙胺类兴奋剂(ATS)的使用以确定柬埔寨年轻女性性工作者自我报告的ATS使用的有效性

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摘要

Objective To assess concordance between self-reported amphetamine-type stimulant (ATS) use and toxicology results among young female sex workers (FSW) in Phnom Penh, Cambodia. Methods Cross-sectional data from the Young Women’s Health Study-2 (YWHS-2), a prospective study of HIV and ATS use among young (15 to 29?years) FSW in Phnom Penh, Cambodia, was analyzed. The YWHS-2 assessed sociodemographic characteristics, HIV serology, HIV risk, and ATS use by self-report and urine toxicology testing at each quarterly visit, the second of which provided data for this assessment. Outcomes include sensitivity, specificity, positive- and negative predictive values (overall and stratified by age), sex-work setting, and HIV status. Results Among 200 women, prevalence of positive toxicology screening for ATS use was 14% (95% confidence interval [CI], 9.2, 18.9%) and concurrent prevalence of self-reported ATS was 15.5% (95% CI, 10.4, 20.6%). The sensitivity and specificity of self-reported ATS use compared to positive toxicology test results was 89.3% (25/28), and 96.5% (166/172), respectively. The positive predictive value of self-reported ATS use was 80.6% (25/31); the negative predictive value was 98.2% (166/169). Some differences in concordance between self-report and urine toxicology results were noted in analyses stratified by age group and sex-work setting but not by HIV status. Conclusion Results indicate a high prevalence of ATS use among FSW in Phnom Penh, Cambodia, and high concordance between self-reported and toxicology-test confirmed ATS use.
机译:目的评估柬埔寨金边年轻女性性工作者(FSW)自我报告的苯丙胺类兴奋剂(ATS)使用与毒理学结果之间的一致性。方法分析了来自年轻女性健康研究2(YWHS-2)的横断面数据,该研究是柬埔寨金边年轻(15至29岁)FSW中艾滋病毒和ATS使用的前瞻性研究。 YWHS-2在每次季度访问时通过自我报告和尿毒理学测试评估了社会人口统计学特征,HIV血清学,HIV风险和ATS的使用,其中第二个为该评估提供了数据。结果包括敏感性,特异性,阳性和阴性预测值(总体和按年龄分层),性工作环境和艾滋病毒状况。结果在200名女性中,使用ATS进行阳性毒理学筛查的患病率为14%(95%置信区间[CI],9.2,18.9%),同时自我报告的ATS流行率为15.5%(95%CI,10.4,20.6%)。 )。与阳性毒理学测试结果相比,自我报告的ATS使用的敏感性和特异性分别为89.3%(25/28)和96.5%(166/172)。自我报告使用ATS的阳性预测值为80.6%(25/31);阴性预测值为98.2%(166/169)。在按年龄组和性工作环境分层但未按艾滋病毒感染状况分层的分析中,发现自我报告和尿毒理学结果之间在一致性方面存在一些差异。结论结果表明,柬埔寨金边的FSW中ATS的使用率很高,而自我报告与毒理学测试确认的ATS的使用之间高度一致。

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